1989 – Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, smjer Molekularna biologija, Dipl.ing.

1992 – Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, smjer Molekularna i stanična biologija, Mr. sc.

1998 – Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu, smjer Molekularna biologija, Dr. sc.

1992 – FEBS stipendija za tečaj “Recombinant DNA technology in human medicine”, Mekedonija, Skopje, 14-26. rujan

1993 – Institute fur Immunologie GSF, Munnich, Njemačka, laboratorij Prof. Dr. Stephan Thierfelder-a,

2006 – training course The protein arrays for biomarker discovery and protein expression profiling, Prag, Češka

Animalni modeli, obavezni kolegij na doktorskom poslijediplomskom studiju Medicinsko-biokemijske znanosti, Farmaceutsko-biokemijskog fakulteta, Sveučilišta u Zagrebu

Personalna medicina-prediktivna medicina i faramkogenetika, neobavezni kolegij na doktorskom poslijediplomskom interdisciplinarnom studiju Molekularne bioznanosti

 Molekularno-genetička osnova tumora gastrointestinalnog trakta, neobavezni kolegij na doktorskom poslijediplomskom studiju Biomedicina i zdravstvo, Medicinski fakultet Sveučilišta u Zagrebu

Predklinička i klinička ispitivanja biljnih pripravaka, obavezni kolegij na doktorskom poslijediplomskom studiju  Farmaceutsko-biokemijske znanosti, Farmaceutsko-biokemijskog fakulteta, Sveučilista u Zagrebu

Kopriva Ivica,  Hadžija Mirko,  Popović-Hadžija Marijana,  Korolija Marina,   Cichocki, Andrzej. Rational variety mapping for contract-enhance nonlinear unsupervised segmentation of multispectral images of unstained specimen. The American Journal of Pathology 179:547-554, 2011

 Korolija Marina,  Hadžija Mirko, Pape Medvidović  Edita, Pavković  Pajica, Kapitanović  Sanja, Pavlić Renar Ivana, Popović Hadžija  Marijana. Genetic evaluation of TNF-a -238G>A and 308G>A promoter polymorphisms in Croatian patients. Human Immunology 71: 1228-1232, 2010

 Popović Hadžija  Marijana,  Korolija Marina, Jakić Razumović  Jasminka, Pavković Pajica,  Hadžija  Mirko,  Kapitanović  Sanja. K-Ras and Dpcr mutations in chronic pancreatitis: Case Series. Croatian Medical Journal 48:218-224, 2007

 Popović Hadžija M. Radošević S, Kovačević D, Lukač J, Hadžija M, Spaventi R, Pavelić K, Kapitanović S: Status of the DPC4 tumor suppressor gene in sporadic colon carcinoma from Croatian patients: identification of a novel somatic mutation. Mutation Research 548: 61-73, 2004

 Popović Hadžija M, Hrašćan R, HerakBosnar M, Zeljko Ž, Hadžija M, Čadež J, Pavelić K, Kapitanović S: Infrequent alteration of the DPC4 tumor suppressor gene in renal cell carcinoma. Urological Research 32:229-235, 2004

 Popović Hadžija M, Kapitanović S, Radošević S, Čačev T, Mirt M, Kovačević D, Lukač J, Hadžija M, Spaventi R, Pavelić K: Loss of heterozygosity of DPC4 tumor suppressor gene in human sporadic colon cancer. Jouranal of Molecular Medicine 79: 128-132, 2001

Knjige i poglavlja u knjigama

Poglavlja u knjigama

• Perina, D., Korolija, M., Popović Hadžija, M., Grbeša, I., Belužić, R., Imešek, M., Morrow, C., Posavec Marjanović, M., Bakran- Petricioli, T., Mikoč, A. & Ćetković, H. (2015) Functional and Structural Characterization of FAU Gene/Protein from Marine Sponge Suberites domuncula. U: Honecker, F. & Dyshlovoy, S. (ur.) Marine Compounds and Cancer. Basel, Switzerland, MDPI Books, str. 700-717. (https://www.bib.irb.hr/989209).

  www.mdpi.comdoi.orgwww.mdpi.comfulir.irb.hr

Radovi u časopisima

Znanstveni i pregledni radovi

• Siketić, Z., Bogdanović Radović, I., Barac, M., Brajković, M. & Popović Hadžija, M. (2023) Chemical Imaging of Organic Materials by MeV SIMS Using a Continuous Collimated Ion Beam. Analytical chemistry, 95 (5), 3069-3074 doi:10.1021/acs.analchem.2c05234.

  doipubs.acs.org

• Pinterić, M., Podgorski, I., Popović Hadžija, M., Tartaro Bujak, I., Tadijan, A., Balog, T. & Sobočanec, S. (2021) Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice. International journal of molecular sciences, 22 (8), 4277, 17 doi:10.3390/ijms22084277.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Kopriva, I., Jerić, I., Popović Hadžija, M., Hadžija, M. & Vučić Lovrenčić, M. (2021) Nonnegative Least Squares Approach to Quantification of 1H Nuclear Magnetic Resonance Spectra of Human Urine. Analytical chemistry, 93 (2), 745-751 doi:10.1021/acs.analchem.0c02837.

  doipubs.acs.orgdoi.orgfulir.irb.hr

• Sitnik, D., Aralica, G., Hadžija, M., Popović Hadžija, M., Pačić, A., Milković Periša, M., Manojlović, L., Krstanaca, K., Plavetić, A. & Kopriva, I. (2021) Dataset and a methodology for intraoperative computer-aided diagnosis of a metastatic colon cancer in a liver. Biomedical Signal Processing and Control, 66, 102402, 11 doi:10.1016/j.bspc.2020.102402.

  doi

• Podgorski, I., Pinterić, M., Marčinko, D., Popović Hadžija, M., Filić, V., Ciganek, I., Pleše, D., Balog, T. & Sobočanec, S. (2020) Combination of sirtuin 3 and hyperoxia diminishes tumorigenic properties of MDA-MB-231 cells. Life sciences, 254, 117812, 13 doi:10.1016/j.lfs.2020.117812.

  doi

• Pinterić, M., Podgorski, I., Popović- Hadžija, M., Filić, V., Paradžik, M., Proust, B., Dekanić, A., Ciganek, I., Pleše, D., Marčinko, D., Balog, T. & Sobočanec, S. (2020) Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells. Antioxidants, 9 (4), 294, 21 doi:10.3390/antiox9040294.

  doiwww.mdpi.comfulir.irb.hr

• Pinterić, M., Podgorski, I., Popović Hadžija , M., Tartaro Bujak, I., Dekanić, A., Bagarić, R., Farkaš, V., Sobočanec, S. & Balog, T. (2020) Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice. Antioxidants, 9 (2), 174, 19 doi:10.3390/antiox9020174.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Kopriva, I., Jerić, I., Popović Hadžija, M., Hadžija, M., Vučić Lovrenčić, M. & Brkljačić, L. (2019) Library-Assisted Nonlinear Blind Separation and Annotation of Pure Components from a Single 1H Nuclear Magnetic Resonance Mixture Spectra. Analytica chimica acta, 1080, 55-65 doi:10.1016/j.aca.2019.07.004.

  doi

• Pinterić, M., Podgorski, I., Sobočanec, S., Popović Hadžija, M., Paradžik, M., Dekanić, A., Marinović, M., Halasz, M., Belužić, R., Davidović, G., Ambriović Ristov, A. & Balog, T. (2018) De novo expression of transfected sirtuin 3 enhances susceptibility of human MCF-7 breast cancer cells to hyperoxia treatment. Free radical research, 52 (6), 672, 684 doi:10.1080/10715762.2018.1462495.

  doiwww.tandfonline.com

• Sobočanec, S., Filić, V., Matovina, M., Majhen, D., Šafranko, Ž., Popović Hadžija, M., Krsnik, Ž., Gudan Kurilj, A., Šarić, A., Abramić, M. & Balog, T. (2016) Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo. Redox Biology, 8, 149-159 doi:10.1016/j.redox.2016.01.003.

  doi

• Sobočanec, S., Mačak Šafranko, Ž., Šarić, A., Korolija, M., Popović Hadžija, M. & Balog, T. (2016) Response to hyperoxia is associated with similar ho-1 gene expression level in lungs of aging CBA mice of both sexes. Biochemistry and biophysics reports, 5, 55-62 doi:10.1016/j.bbrep.2015.09.002.

  doiwww.sciencedirect.com

• Šarić, A., Sobočanec, S., Mačak Šafranko, Ž., Popović Hadžija, M., Bagarić, R., Farkaš, V., Švarc, A., Marotti, T. & Balog, T. (2015) Diminished resistance to hyperoxia in brains of reproductively senescent female CBA/H mice. Medical science monitor basic research, 21, 191-199 doi:10.12659/MSMBR.895356.

  doibasic.medscimonit.comfulir.irb.hr

• Perina, D., Korolija, M., Popović Hadžija, M., Grbeša, I., Belužić, R., Imešek, M., Morrow, C., Posavec Marjanović, M., Bakran-Petricioli, T., Mikoč, A. & Ćetković, H. (2015) Structural Characterization of FAU Gene/Protein from Marine Sponge Suberites domuncula. Marine drugs, 13 (7), 4179-4196 doi:10.3390/md13074179.

  doifulir.irb.hr

• Siketić, Z., Bogdanović Radović, I., Jakšić, M., Popović Hadžija, M., Hadžija, M. & (2015) Submicron mass spectrometry imaging of single cells by combined use of mega electron volt time-of-flight secondary ion mass spectrometry and scanning transmission ion microscopy. Applied physics letters, 107, 093702-1 doi:10.1063/1.4930062.

  doi

• Kopriva, I., Popović Hadžija, M., Hadžija, M. & Aralica, G. (2015) Offset-sparsity decomposition for automated enhancement of color microscopic image of stained specimen in histopathology. Journal of biomedical optics, 20 (7), 076012-1 doi:10.1117/1.JBO.20.7.076012.

  doifulir.irb.hr

• Nikolić, A., Čačev, T., Aralica, G., Popović Hadžija, M., Kapitanović, S. & Radojković, D. (2015) Mononucleotide repeats in the SMAD4 gene promoter in colon carcinoma tissue of Croatian patients. Experimental and molecular pathology, 98 (2), 133-135 doi:10.1016/j.yexmp.2015.02.008.

  doi

• Kopriva, I., Popović Hadžija, M., Hadžija, M. & Aralica, G. (2015) Unsupervised segmentation of low-contrast multichannel images: discrimination of tissue components in microscopic images of unstained specimens. Scientific Reports, 5, 11576-1 doi:10.1038/srep11576.

  doifulir.irb.hr

• Sobočanec, S., Šarić, A., Mačak Šafranko, Ž., Popović Hadžija, M., Abramić, M. & Balog, T. (2015) The role of 17 Beta-estradiol in the regulation of antioxidant enzymes via the nrf2-keap1 pathway in livers of CBA/H mice. Life sciences, 130, 57-65 doi:10.1016/j.lfs.2015.03.014.

  doi

• Šarić, A., Sobočanec, S., Mačak-Šafranko, Ž., Popović-Hadžija, M., Aralica, G., Korolija, M., Kušić, B. & Balog, T. (2014) Female headstart in resistance to hyperoxia-induced oxidative stress. Acta biochimica Polonica, 61 (4), 801-807.

• Popović Hadžija, M., Korolija, M., Vukadinović, G. & Hadžija, M. (2013) Association of TNF-α and PTPN22 SNPs with the risk and clinical outcome of type 1 diabetes. Central european journal of biology, 8, 513-519 doi:10.2478/s11535-013-0166-5.

  doi

• Popović Hadžija, M., Korolija, M., Jemin, N., Pavković, I., Pavković, P., Pape Medvidović, E. & Hadžija, M. (2013) Polymorphisms in the IL-18 and IL-12B genes and their association with the clinical outcome in Croatian patients with Type 1 diabetes. Gene, 512 (2), 477-481 doi:10.1016/j.gene.2012.10.02.

  doi

• Mustapić, M., Popović-Hadžija, M., Pavlović, M., Pavković, P., Presečki, P., Mrazovac, D., Mimica, N., Korolija, M., Pivac, N. & Muck-Šeler, D. (2012) Alzheimer's disease and type 2 diabetes: The association study of polymorphisms in tumor necrosis factor-alpha and apolipoprotein E genes. Metabolic brain disease, 27 (4), 507-512 doi:10.1007/s11011-012-9310-1.

  doi

• Kopriva, I., Hadžija, M., Popović-Hadžija, M., Korolija, M. & Cichocki, A. (2011) Rational Variety Mapping for Contrast-Enhanced Nonlinear Unsupervised Segmentation of Multispectral Images of Unstained Specimen. American journal of pathology, 179 (2), 547-554 doi:10.1016/j.ajpath.2011.05.010.

  doi

• Korolija, M., Hadžija, M., Pape Medvidović, E., Pavković, P., Kapitanović, S., Pavlić Renar, I. & Popović Hadžija, M. (2010) Genetic evaluation of the TNF-α -238G>A and -308G>A promoter polymorphisms in croatian patients with type i diabetes. Human immunology, 71 (12), 1228-1232 doi:10.1016/j.humimm.2010.09.003.

  doi

• Korolija, M., Pavlić Renar, I., Hadžija, M., Pape Medvidović, E., Pavković, P., Jokić, M. & Popović Hadžija, M. (2009) Association of PTPN22 C1858T and CTLA-4 A49G Polymorphisms with Type 1 Diabetes in Croatians. Diabetes research and clinical practice, 86 (3), e54-e57 doi:10.1016/j.diabres.2009.09.012.

  doi

• Korolija, M., Popović Hadžija, M. & Hadžija, M. (2009) Molecular mechanism in β -cells development: the role of PDX1, Ngn3 and Pax4 proteins. Periodicum biologorum, 111 (1), 59-63.

  hrcak.srce.hr

• Korolija, M., Hadžija, M., Pavković, P., Kapitanović, S. & Popović Hadžija, M. (2008) Improved performances of polyacrylamide gel by addition of a new type of polymer: detection of allelic losses. Croatica Chemica Acta, 81 (3), 437-441.

• Popović Hadžija, M., Korolija, M., Jakić Razumović, J., Pavković, P., Hadžija, M. & Kapitanović, S. (2007) K-Ras and Dpc4 Mutations in Chronic Pancreatitis: Case Series. Croatian Medical Journal, 48 (2), 218-224.

• Korolija, M., Popović-Hadžija, M. & Hadžija, M. (2006) Rapid loss of pluripotency regulator Oct4 expression in cultured embryonic stem cells of non-obese diabetic mice. Periodicum biologorum, 108 (5), 567-570.

• Kapitanović, S., Čačev, T., Berković, M., Popović Hadžija, M., Radošević, S., Seiwerth, S., Spaventi, Š., Pavelić, K. & Spaventi, R. (2004) nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma. Journal of clinical pathology, 57 (12), 1312-1318 doi:10.1136/jcp.2004.017954.

  doi

• Popović Hadžija, M., Radoševic, S., Kovačević, D., Lukač, J., Hadžija, M., Spaventi, R., Pavelić, K. & Kapitanović, S. (2004) Status of the DPC4 tumor suppressor gene in sporadic colon adenocarcinoma of croatian patients: identification of a novel somatic mutation. Mutation research, 548, 61-73.

• Popović Hadžija, M., Hrašćan, R., Herak Bosnar, M., Zeljko, Ž., Hadžija, M., Čadež, J., Pavelić, K. & Kapitanović, S. (2004) Alterations of the DPC4 tumor-suppressor gene in renal cell carcinoma. Urological research, 32 (3), 229-235.

• Popović Hadžija, M., Poljak-Blaži, M. & Hadžija, M. (2002) Resistance of mouse myeloid leukemia cells to apoptosis: involving of c-Myc, Bcl-2 and p53. Periodicum biologorum, 104 (4), 381-387.

• Pavelić, K., Križanac, Š., Čačev, T., Popović Hadžija, M., Crnić, I., Levanat, S. & Kapitanović, S. (2001) Aberration of FHIT gene associated with increased tumor proliferation and decreased apoptosis - clinical evidence in lung and head and neck carcinomas. Molecular Medicine, 7 (7), 442-453.

• Popović Hadžija, M., Kapitanović, S., Radošević, S., Čačev, T., Mirt, M., Kovačević, D., Lukač, J., Hadžija, M., Spaventi, R. & Pavelić, K. (2001) Loss of heterozygosity of DPC4 tumor suppressor gene in human sporadic colon cancer. Journal of Molecular Medicine, 79 (2-3), 128-132.

• Poljak-Blaži, M., Kralj, M., Popović Hadžija, M., Žarković, N., Žarković, K. & Waeg, G. (2000) Involvement of lipid peroxidation, oncogene expression and induction of apoptosis in the antitumorous activity of ferric-sorbitol-citrate. Cancer Biotherapy & Radiopharmaceuticals, 15, 285-293.

• Popović Hadžija, M. & Poljak Blaži, M. (1998) Differential expression of Bcl-2 protein in non-irradiated or UVC-irradiated murine myeloid leukemia (ML) cells. Radiology and oncology, 32 (1), 47-52.

• Popović Hadžija, M., Poljak-Blaži, M. & Pavelić, K. (1997) Presence of c-myc protein in murine myeloid leukaemia cells during growth and after irradiation. Anticancer research, 17 (2A), 1089-1092.

• Poljak-Blaži, M., Popović, M. & Majić, T. (1994) The mechanism of recurrence of mouse myeloid leukaemia after total body irradiation and bone marrow transplantation. Oncology-new york, 51 (3), 282-287 doi:10.1159/000227350.

  doi

• Poljak-Blaži, M., Popović, M. & Osmak, M. (1992) Malignant transformation of bone marrow cells by nuclei and supernatant of kolled murine myeloid leukemia cells. Periodicum biologorum, 94, 201-208.

Radovi u zbornicima skupova

Znanstveni radovi u zbornicima skupova

• Kopriva, I., Sitnik, D., Aralica, G., Paćić, A., Popović Hadžija, M., Hadžija, M. & (2021) Approximate explicit feature map for computational augmentation of RGB images of hematoxylin and eosin stained histopathological specimens. U: Tomaszevski, J. & Ward, A. (ur.)Medical Imaging 2021: Digital Pathology, vol. 11603 doi:10.1117/12.2579408.

  doi

• Sitnik, D., Aralica, G., Pačić, A., Popović Hadžija, M., Hadžija, M. & Kopriva, I. (2020) Deep learning approaches for intraoperative pixel-based diagnosis of colon cancer metastasis in a liver from phase-contrast images of unstained specimens. U: Tomaszewski, J. & Ward, A. (ur.)Digital Pathology Conference - SPIE Medical Imaging Symposium 2020 doi:10.1117/12.2542799.

  doi

• Sitnik, D., Kopriva, I., Aralica, G., Pačić, A., Popović Hadžija, M. & Hadžija, M. (2020) Transfer Learning Approach for Intraoperative Pixel-based Diagnosis of Colon Cancer Metastasis in a Liver from Hematohylin-Eosin Stained Specimens. U: Tomaszewski, J. & Ward, A. (ur.)Proceedings Volume 11320, Medical Imaging 2020: Digital Pathology ; 1132009 (2020) doi:10.1117/12.2538303.

  doi

• Kopriva, I., Aralica, G., Popović Hadžija, M., Hadžija, M., Dion-Bertrand, L. & Chen, X. (2019) Hyperspectral imaging for intraoperative diagnosis of colon cancer metastasis in a liver. U: Tomaszewski, J. & Ward, A. (ur.)SPIE Medical Imaging Symposium 2019 - Digital Pathology Conference doi:10.1117/12.2503907.

  doi

• Poljak-Blaži, M., Kralj, M. & Popović Hadžija, M. (2000) Oncogene activation and apoptosis as possible mechanism of antitumour effect of ferric-sorbitol-citrate. U: Roussel, A., Anderson, R. & Favier, A. (ur.)Proceedings of the 10th International Symposium on Trace Elements in Man and Animal (TEMA 10).

• Poljak Blaži, M., Prutki, M., Popović Hadžija, M. & Hadžija, M. (1996) Imunosupresivno i karcinogeno djelovanje UV svjetla : apoptoza i liza stanica slezene zdravih miševa nakon izlaganja UVC svjetlu = Immunosuppressive and carcinogenic effect of UV-light : apoptosis and lysis of mice spleen cells. U: Kubelka, D. & Kovač, J. (ur.)Zbornik radova trećeg simpozija Hrvatskog društva za zaštitu od zračenja = Proceedings of the Symposium of the Croatian Radiation Protection Association.

• Popović Hadžija, M. & Poljak-Blaži, M. (1996) Utjecaj x-zračenja i UV-svjetla na prisutnost onkogenih proteina u stanicama slezene leukemičnih miševa = Influence of x-rays and UV-light on the presence of oncogene proteins in spleen cells of leukemic mice. U: Kubelka, D. & Kovač, J. (ur.)Zbornik radova trećeg simpozija Hrvatskog društva za zaštitu od zračenja = Proceedings of the Symposium of the Croatian Radiation Protection Association.

• Popović Hadžija, M. & Poljak-Blaži, M. (1996) Presence of c-myc protein during maturation of murine myeloid leukaemia (ML) and after x- or UV-irradiation of ML cells. U: Osmak, M. & Škrk, J. (ur.)Molecular oncology today : proceedings of the Croatian-Slovenian meeting.

Patenti

• Basic Robert (2005) Inhibitors of apoptosis of nerve cells, US Patent 6953595.

• Bašić Robert (2005) Composition comprising clinoptolite, plant extracts and vitamin b complex for diabetic neuropathy, WO0195920 (A1).

Hrvatska zeolitna udruga

Hrvatsko društvo fiziologa