1987. Doktor prirodnih znanosti iz područja imunologije, Biološki fakultet "Ludwig Maximilian"  Sveučilište u Münchenu, SR Njemačka

1983. Magistar prirodnih znanosti, Poslijediplomski studij prirodnih znanosti, Smjer molekularna biologija, Sveučilište u Zagrebu

Znanstveni projekti:

01/07/2020 – 18/10/2022 Healthcareonline-HERO, Central European Initiative (CEI) COVID-19 Extraordinary Call for Proposals 2020, principal investigator https://health-online-hero.com/

2021 – 2025 Hrvatska zaklada za znanost, IP-2020-02- 2431 Obnova timusa za preciznu medicinu u liječenju tumora i leukemija, glavni istraživač

2017-2022 Suradnik na projektu: Znanstveni centar izvrsnosti za reproduktivnu i regenerativnu medicinu (CERRM), Biomedicinsko istraživanje reprodukcije i razvoja, voditelj prof. dr. sc. Davor Ježek i Regenerativna medicina, voditelj akademik Slobodan Vukičević, sredstva Europske Komisije, EC

2013 - 2017 European Commission 7th Framework Programme “Thymistem”, voditelj hrvatskog tima

2014 - 2018 Istraživački projekt Hrvatske zaklade za znanost, voditelj

2015 -2016 Bilateralni međunarodni Hrvatsko - Kineski projekt, voditelj

2014 -2018 Projekt razvoja karijera mladih istraživača - izobrazba novih doktora znanosti Hrvatske zaklade za znanost, voditelj

1995 - 2013 Voditelj završenih znanstvenih projekata: 4 međunarodna i 5 nacionalna

1987. Državna nagrada za znanstveni rad  za mlade znanstvenike         

1999. Nagrada HAZU za doprinos od osobitog i trajnog značenja za Republiku Hrvatsku u području medicinskih znanosti                

2000. Godišnja Državna nagrada za znanost          

2008. Nagrada Hrvatskog imunološkog društva za najbolju znanstvenu publikaciju člana u toj godini

2012. Nagrada Instituta Ruđer Bošković za uredništvo knjige: "Acute leukemia- The scientist's perspective and challenge", Intech,

Voditelj ¸i osnivač kolegija na  Poslijediplomskom studiju na

Prirodoslovno matematičkom fakultetu,

Medicinskom fakultetu u Zagrebu i Osijeku

Međunarodnom studiju, Orleans, Francuska

1. V. Shichkin and M. Antica (2020) Thymus regeneration and future challenges. Stem Cell Reviews and Reports (29.1.2020. Epub ahead of print)
2. M. Antica, & J. Skelin, (2019) Current trends in targeted therapy of leukaemia and lymphoma Advances in General Practice of Medicine, 2(1), 16-18.               
3. R. Ribić, R. Stojković, L. Milković, M. Antica, M. Cigler and S. Tomić (2019)  Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides  Beilstein Journal of Organic Chemistry 15, 1805–1814.
4. L. Horvat, M. Grubar, J. Madunic, M. Antica, M. Matulić (2019) Inhibition of PARP activity does not affect the differentiation processes caused by retinoic acid in SH-SY5Y cells. Molecular and experimental biology in medicine 2 (1), 38-43. 
5. L. Horvat, J. Skelin, B. Jelić Puškarić, I. Feliciello, D. Heckel, J. Madunić, I. Kardum-Skelin, M. Matulić,  D. Radić-Krišto and M. Antica (2018) Notch pathway connections in primary leukaemia samples of limited size Translational Medicine Communications  3:8 5.
6. L. Horvat , M. Antica and M. Matulić (2018) Effect of Notch and PARP Pathways’ Inhibition in Leukemic Cells. Cells, 7(6), 58; 
7. J. Madunić, L. Horvat, I. Majstorović, I. Jodłowska, M.  Antica, M.  Matulić (2017) Sodium Salicylate Inhibits Urokinase Activity in MDA MB-231 Breast Cancer Cells. Clinical breast cancer. 17, (8):  629-637
8. J. Madunić , M. Antica, P. Cvjetko, L. Požgaj, M. Matulić (2016) Modulation of urokinase plasminogen activator system by poly(ADP-ribose)polymerase-1 inhibition. Cytotechnology. 68.4 : 783-794.
9. M. Matulić, J. Skelin, D. Radic-Krišto, I. Kardum-Skelin, D. Grčević, M. Antica(2015) Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry A. 87 129-136.  and M. Antica (2015) Notched player in myeloid leukemia - new insights exposed, In this issue. Cytometry A, 87: NA. doi: 10.1002/cyto.a.22530
10. A. J. Martić, S. Ivanković, M. Antica, N. Hiršl, T. Jukić, M. Jurin (2015) Transplanted tumor growth and the incidence of T-lymphocyte populations in the spleen of newcastle virus-treated mice. Cancer Biother Radiopharm. 30(4):182-186.
11. M. Matulic, Paradzik, M., Cicin-Sain, L., Kapitanovic, S., Dubravcic, K., Batinic, D., Antica, M. (2009) Ikaros family transcription factors in chronic and acute leukemia. Am J Hematol. 84, 375-377
12. M. Antica, L. Cicin-Sain, S. Kapitanovic, M. Matulić, S. Dzebro and M. Dominis (2008) Aberrant Ikaros, Aiolos and Helios expression in Hodgkin and non-Hodgkin lymphoma.  Blood 111 3296 - 3297.
13. M. Antica, Dubravcic, K., Rajic, LJ., Labar, B., Batinic, D. (2007) A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from leukemia patients. Haematologica Haematologica. 92 260-261
14. M.Antica, B. Kusic, D. Hranilovic, A.B. Dietz, and S. Vuk-Pavlovic (2002) Cloning the cDNA for murine U2 snRNP-A' gene and its differential expression in lymphocyte development. Immunol. Letters, 82 (3) 217-223 
15. M. Antica, R. Scollay (1999) Development of T lymphocytes at extrathymic sites.  J. Immunol., 163 206-211.
16. J. Ismaili, M. Antica and L. Wu (1996) CD4 and CD8 expression and T cell antigen receptor gene rearrangement in early intrathymic precursor cells. Eur. J. Immunol. 26 731-737.
17. M. Antica L. Wu, K. Shortman and R. Scollay (1994) Thymic stem cells in the mouse bone marrow. Blood 84, 111-117
18. M. Antica L. Wu, K. Shortman and R. Scollay (1993) Intrathymic lymphoid precursor cells during fetal thymus development. J. Immunol.151, 1-9
19. L. Wu, M. Antica G. R. Johnson, R. Scollay and K. Shortman (1991) Developmental potential of the earliest precursor cells from the adult mouse thymus. J. Exp. Med174, 1617 – 1627

Uredništvo i prijevod knjige:

      Tvoj čudesni imunosni sustav, (2016) ISBN: 978-953-7941-09-3,  M. Antica (Ed.) 

Knjige i poglavlja u knjigama

Autorske knjige

• Menac, A., Fink-Arsovski, Ž., Mironova Blažina, I. & Venturin, R. (2011) Hrvatsko-ruski frazeološki rječnik : kazalo hrvatskih i ruskih frazema = Horvatsko-russkii frazeologičeskii slovary = ukazatel’ horvatskih i russkih frazeologizmov. Zagreb, Knjigra.

Knjige i poglavlja u knjigama

Poglavlja u knjigama

• Antica, M. (2011) Lymphocyte commitment and Ikaros transcription factors. U: Antica, M. (ur.) Acute Leukemia - the Scientist's Perspective and Challenge. Rijeka, Intech, str. 69-74 doi:10.5772/19794.

  doi

• Antica, M. (1997) Razvoj limfocita u kulturama fetalnih tumisa. U: Stavljenić-Rukavina, A., Batinić, D. & Bilić-Zulle, L. (ur.) Protočna citometrija u kliničkolaboratorijskoj praksi., Medicinski fakultet Sveučilišta u Zagrebu : KBC, str. 83-89.

• Scollay, R. & Antica, M. (1995) Stem cells for lymphocytes: comments on the time and place of commitment of precursors for the T lineage. U: Ikehara, F., Takaku, R. & Good, A. (ur.) Bone Marrow Transplantation, Basic and Clinical Studies., Springer Verlag, str. 20-28.

• Antica, M. & Spaventi, R. (1989) Onkogen c-myc u normalnoj i u zloćudno preobraženoj stanici. U: Ikić, D., Pavelić, K. & Spaventi, R. (ur.) Onkogeni i faktori rasta. Zagreb, Jugoslavenska akademija znanosti i umjetnosti : Globus, str. -.

Radovi u časopisima

Znanstveni i pregledni radovi

• Filipović, M., Flegar, D., Šućur, A., Šisl, D., Kavazović, I., Antica, M., Kelava, T., Kovačić, N. & Grčević, D. (2022) Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions. Frontiers in Immunology, 13, 902947, 19 doi:10.3389/fimmu.2022.902947.

  doiwww.frontiersin.orgdoi.orgfulir.irb.hr

• Shichkin, V. & Antica, M. (2022) Key Factors for Thymic Function and Development. Frontiers in Immunology, 13, 926516, 18 doi:10.3389/fimmu.2022.926516.

  doiwww.frontiersin.org

• Korać, P., Antica, M. & Matulić, M. (2021) MiR-7 in Cancer Development. Biomedicines, 9 (3), 325, 20 doi:10.3390/biomedicines9030325.

  doiwww.mdpi.comfulir.irb.hr

• Petrović Peroković, V., Car, Ž., Draženović, J., Stojković, R., Milković, L., Antica, M., Škalamera, Đ., Tomić, S. & Ribić, R. (2021) Design, Synthesis, and Biological Evaluation of Desmuramyl Dipeptides Modified by Adamantyl-1,2,3-triazole. Molecules, 26 (21), 6352, 13 doi:10.3390/molecules26216352.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Jukić, T., Jurin Martić, A., Ivanković, S., Antica, M., Pavan Jukić, D., Rotim, C. & Jurin, M. (2020) The role of regulatory T Lymphocytes in immune control of MC-2 Fibrosarcoma. Acta clinica Croatica, 59 (2), 351-358 doi:10.20471/acc.2020.59.02.20.

  doiactaclinica.euhrcak.srce.hrfulir.irb.hr

• Kolić, D., Horvat, L., Šetinc, M., Antica, M. & Matulić, M. (2020) miR-7 AND miR-34a sequence cloning and expression in a1235 glioblastoma cell line. Molecular and experimental biology in medicine, 3 (2), 31-38 doi:10.33602/mebm.3.2.4.

  doimebm.eumebm.eudoi.orgfulir.irb.hr

• Shichkin, V. & Antica, M. (2020) Thymus Regeneration and Future Challenges. Stem cell reviews and reports, 16, 239-250 doi:10.1007/s12015-020-09955-y.

  doilink.springer.comfulir.irb.hr

• Horvat, L., Antica, M. & Matulić, M. (2020) The Effect of Casein Kinase 2 Inhibition on three Leukemic Cell Lines. Current drug therapy, 15 (3), 209-215 doi:10.2174/1574885514666190724111509.

  doi

• Ribić, R., Stojković, R., Milković, L., Antica, M., Cigler, M. & Tomić, S. (2019) Design, synthesis and biological evaluation of immunostimulating mannosylated desmuramyl peptides. Beilstein journal of organic chemistry, 15, 1805-1814 doi:10.3762/bjoc.15.174.

  doifulir.irb.hrwww.beilstein-journals.orgdoi.org

• Horvat, L., Madunić, J., Grubar, M., Antica, M. & Matulić, M. (2019) Induction of Urokinase Activity by Retinoic Acid in Two Cell Lines of Neuronal Origin. Biomedicines, 7 (3), 70, 15 doi:10.3390/biomedicines7030070.

  doidoi.orgwww.mdpi.comwww.mdpi.comfulir.irb.hr

• Skelin, J. & Antica, M. (2019) Current trends in targeted therapy of leukaemia and lymphoma. Advances in General Practice of Medicine, 2 (1), 16-18 doi:10.25082/AGPM.2019.01.005.

  doiwww.syncsci.comdoi.orgfulir.irb.hr

• Horvat, L., Grubar, M., Madunić, J., Antica, M. & Matulić, M. (2019) Inhibition of PARP activity does not affect the differentiation processes caused by retinoic acid in SH-SY5Y cells. Molecular and Experimental Biology in Medicine, 2 (1), 38-43. (https://www.bib.irb.hr/993892).

  mebm.eu

• Horvat, L., Antica, M. & Matulić, M. (2018) Effect of Notch and PARP Pathways’ Inhibition in Leukemic Cells. Cells, 7 (6), 58-70 doi:10.3390/cells7060058.

  doifulir.irb.hrwww.ncbi.nlm.nih.govwww.mdpi.comdoi.org

• Horvat, L., Skelin, J., Puškarić, B., Feliciello, I., Heckel, D., Madunić, J., Kardum-Skelin, I., Matulić, M., Radić-Krišto, D. & Antica, M. (2018) Notch pathway connections in primary leukaemia samples of limited size. Translational Medicine Communications, 3, 8, 9 doi:10.1186/s41231-018-0026-z.

  doitransmedcomms.biomedcentral.comfulir.irb.hrdoi.org

• Madunić, J., Horvat, L., Majstorović, I., Jodłowska, I., Antica, M. & Matulić, M. (2017) Sodium Salicylate Inhibits Urokinase Activity in MDA MB-231 Breast Cancer Cells. Clinical breast cancer, 17 (8), 629-637 doi:10.1016/j.clbc.2017.03.015.

  doi

• Madunić, J., Antica, M., Cvjetko, P., Požgaj, L. & Matulić, M. (2016) Modulation of urokinase plasminogen activator system by poly(ADP-ribose)polymerase-1 inhibition. Cytotechnology, 68, 783-794 doi:10.1007/s10616-014-9829-6.

  doi

• Jurin Martić, A., Ivanković, S., Antica, M., Hiršl, N., Jukić, T. & Jurin, M. (2015) Transplanted Tumor Growth and the Incidence of T-Lymphocyte Populations in the Spleen of Newcastle Virus-Treated Mice. Cancer biotherapy & radiopharmaceuticals, 30 (4), 182-186 doi:10.1089/cbr.2014.1787.

  doi

• Matulić, M., Skelin, J., Radić-Kristo, D., Kardum-Skelin, I., Grčević, D. & Antica, M. (2015) Notch affects the prodifferentiating effect of retinoic acid and PMA on leukemic cells. Cytometry part a, 87 (2), 129-136 doi:10.1002/cyto.a.22582.

  doi

• Paradžik, M., Novak, S., Mokrović, G., Bordukalo Nikšić, T., Heckel, D., Stipić, J., Pavičić Baldani, D., Čičin-Šain, L. & Antica, M. (2012) Ikaros family transcription factors expression in rat thymus : detection of impaired development. International journal of immunopathology and pharmacology, 25 (4), 893-900 doi:10.1177/039463201202500407.

  doiwww.biolifesas.org

• Antica, M., Paradžik, M., Novak, S., Džebro, S. & Dominis, M. (2010) Gene expression in formalin-fixed paraffin-embedded lymph nodes. Journal of immunological methods, 359 (1/2), 42-46 doi:10.1016/j.jim.2010.05.010.

  doi

• Matulić, M., Paradžik, M., Jelić Puškarić, B., Stipić, J. & Antica, M. (2010) Analysis of Ikaros Family Splicing Variants in Human Hematopoietic Lineages. Collegium antropologicum, 34 (1), 59-62.

  hrcak.srce.hr

• Gavella, M., Garaj-Vrhovac, V., Lipovac, V., Antica, M., Gajski, G. & Nikica, C. (2010) Ganglioside GT1b protects human spermatozoa from hydrogen peroxide-induced DNA and membrane damage. International journal of andrology, 33 (3), 536-544 doi:10.1111/j.1365-2605.2009.00962.x.

  doi

• Matulić, M., Paradžik, M., Čičin-Šain, L., Kapitanović, S., Dubravčić, K., Batinić, D. & Antica, M. (2009) Ikaros family transcription factors in chronic and acute leukemia. American journal of hematology, 84 (6), 375-377 doi:10.1002/ajh.21401.

  doidoi.org

• Antica, M., Čičin-Šain, L., Kapitanović, S., Matulić, M., Džebro, S. & Dominis, M. (2008) Aberrant Ikaros, Aiolos, and Helios expression in Hodgkin and non-Hodgkin lymphoma. Blood, 111 (6), 3296-3297.

• Antica, M., Dubravčić, K., Weber, I., Rajić, L., Labar, B. & Batinić, D. (2007) A search for a mutation of the Aiolos phosphorylation domain in lymphocytes from patients with leukemia. Haematologica, 92 (2), 260-261.

• Kapitanović, S., Čačev, T., Antica, M., Kralj, M., Cavrić, G., Pavelić, K. & Spaventi, R. (2006) Effect of indomethacin on E-cadherin and β-catenin expression in HT-29 colon cancer cells. Experimental and molecular pathology, 80 (1), 91-96 doi:10.1016/j.yexmp.2005.04.008.

  doi

• Kušić, B., Dominis, M., Džebro, S. & Antica, M. (2003) Molecular insight into the diagnosis of lymphoma. International journal of molecular medicine, 12 (4), 667-671 doi:10.3892/ijmm.12.4.667.

  doi

• Vitale, B., Martinis, M., Antica, M., Kušić, B., Rabatić, S., Gagro, A., Kušec, R. & Jakšić, B. (2003) Prolegomenon for chronic lymphocytic leukaemia. Scandinavian journal of immunology, 58 (6), 588-600 doi:10.1111/j.1365-3083.2003.01331.x.

  doi

• Kušić, B., Gašparov, S., Katičić, M., Dominis, M. & Antica, M. (2003) Monolconality in Helicobacter pylori-positive gastric biopsies : an early detection of mucosa-associated lymphoid tissue lymphoma. Experimental and molecular pathology, 74 (1), 61-67 doi:10.1016/S0014-4800(03)80009-6.

  doi

• Korbler, T., Gršković, M., Dominis, M. & Antica, M. (2003) A Simple method for RNA isolation from formalin fixed and paraffin embedded lymphatic tissues. Experimental and molecular pathology, 74 (3), 336-340 doi:10.1016/S0014-4800(03)00024-8.

  doi

• Antica, M., Kušić, B., Hranilović, D., Dietz, A. & Vuk-Pavlović, S. (2002) Cloning the cDNA for murine U2 snRNP-A' gene and its differential expression in lymphocyte development. Immunology Letters, 82 (3), 217-223.

• Antica, M. & Scollay, R. (1999) Development of T lymphocytes at extrathymic sites. Journal of immunology, 163 (1), 206-211.

  www.jimmunol.org

• Dominis, M., Džebro, S., Kušić, B. & Antica, M. (1998) Inflammatory pseudotumor of the spleen. Acta cytologica, 42 (4), 1053-1056.

• Antica, M., Wu, L. & Scollay, R. (1997) Stem cell antigen 2 expression in adult and developing mice. Immunology letters, 55 (1), 47-51 doi:10.1016/S0165-2478(96)02682-X.

  doi

• Ismaili, J., Antica, M. & Wu, L. (1996) CD4 and CD8 expression and T cell antigen receptor gene rearrangement in early intrathymic precursor cells. European journal of immunology, 26 (4), 731-737 doi:10.1002/eji.1830260402.

  doi

• Li, C., Wu, L., Antica, M., Shortman, K. & Johnson, G. (1995) Purified murine long-term in-vivo hematopoietic repopulating cells are not prothymocytes. Experimental hematology, 23 (1), 21-25.

• Antica, M., Wu, L., Shortman, K. & Scollay, R. (1994) Thymic stem-cells in mouse bone-marrow. Blood, 84 (1), 111-117 doi:10.1182/blood.V84.1.111.111.

  doiwww.bloodjournal.org

• Antica, M., Kušić, B., Spaventi, R., Jakšić, B. & Vitale, B. (1993) Functional differences of T cells in B-chronic lymphocytic leukemia. Leukemia & lymphoma, 9 (4-5), 133-140 doi:10.3109/10428199309148516.

  doi

• Antica, M., Wu, L., Shortman, K. & Scollay, R. (1993) Intrathymic lymphoid precursor cells during fetal thymus development. Journal of immunology, 151 (11), 5887-5895.

• Gabrilovac, J., Antica, M. & Osmak, M. (1992) In vivo bidirectional regulation of mouse natural killer (NK) cell cytotoxic activities by Leu-enkephalin: Reversibility by naloxone. Life sciences, 50 (1), 29-37 doi:10.1016/0024-3205(92)90194-T.

  doi

• Wu, L., Antica, M., Johnson, G., Scollay, R. & Shortman, K. (1991) Developmental potential of the earliest precursor cells from the adult-mouse thymus. The Journal of experimental medicine, 174, 1617-1627 doi:10.1084/jem.174.6.1617.

  doijem.rupress.orgwww.ncbi.nlm.nih.gov

• Spaventi, R., Antica, M. & Pavelić, K. (1990) Insulin and insulin-like growth factor I (IGF I) in early mouse embryogenesis. Development (Cambridge), 108, 491-495.

• Antica, M., Hoffmann-Fezer, G. & Thierfelder, S. (1989) Antilymphocytic antibodies and marrow transplantation. 9. T cell depletion in marrow donors with C1q high and low affine antibodies for suppression of GVHD in fully mismatched mice. Experimental hematology, 17 (9), 942-947.

• Hoffmann-Fezer, G., Antica, M., Schuh, R. & Thierfelder, S. (1989) Distribution of injected anti-Thy-1 monoclonal antibodies in mouse lymphatic organs: Evidence for penetration of the cortical blood-thymus barrier, and for intravascular antibody-binding onto lymphocytes. Hybridoma, 8 (5), 517-527 doi:10.1089/hyb.1989.8.517.

  doi

• Antica, M., Heiss, M., Kummer, U., Munker, R., Thiel, E. & Thierfelder, S. (1986) Simultaneous Demonstration of two Antigens on Single T cells using Antibodies with Contrasting Labels. Journal of immunological methods, 87 (2), 129-136 doi:10.1016/0022-1759(86)90521-1.

  doi

• Mariastefania, A., Jakšić, B. & Vitale, B. (1986) T-Lymphocyte Colonies from Patients with Chronic Lymphocytic Leukemia (CLL). Periodicum biologorum. Supplement, 88 (suppl.), 503-504.

Radovi u zbornicima skupova

Znanstveni radovi u zbornicima skupova

• Antica, M. (1997) T lymphocyte development and commitment. U: Dorić, M. (ur.)Pathogenesis of Infectious Diseases.

Doživotni član Međunarodnog društva za kontrolu raka (Union Internationale Contre le Cancer, UICC), od 1992

Članstvo i aktivnost u Međunarodnom društvu za unapređenje citometrije (The International Society for Advancement of Cytometry, ISAC)

Članstvo i aktivnost u Hrvatskom imunološkom društvu (HID), dopredsjednica 1996-2000, član Malog vijeća 2001-2006,

Član Internacionalnog društva za kliničku immunologiju (Federation of Clinical Immunology Societies,FOCIS), od 2012

Član Etičkog povjerenstva Hrvatskog imunološkog društva, od 2015        

Član Europskog društva za istraživanje raka (European Assotiation for Cancer Research, EACR),od 1996. i i veleposlanik od 2015.