dr. sc. Darko Kontrec
D
K
Bijenička cesta br. 54
10000 Zagreb
Republika Hrvatska
Obrazovanje
diplomirani inženjer kemije; Sveučilište u Zagrebu; Prirodoslovno-matematički fakultet; 1992.
magistar prirodnih znanosti (kemija); Sveučilište u Zagrebu; Prirodoslovno-matematički fakultet; 1996.
doktor prirodnih znanosti (kemija); Sveučilište u Zagrebu; Prirodoslovno-matematički fakultet; 1999.
Istaknute publikacije
Publikacije
Radovi u časopisima
Znanstveni i pregledni radovi
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Klarić, D., Pocrnić, M., Lež, D., Polović, S., Kontrec, D., Kosalec, I., Budimir, A. & Galić, N. (2022) Search for new antimicrobials: spectroscopic, spectrometric, and in vitro antimicrobial activity investigation of Ga(III) and Fe(III) complexes with aroylhydrazones. Journal of biological inorganic chemistry, 27, 715-729 doi:10.1007/s00775-022-01967-y.
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Jurin, M., Kontrec, D., Dražić, T. & Roje, M. (2022) Enantioseparation of syn- and anti-3,5-Disubstituted Hydantoins by HPLC and SFC on Immobilized Polysaccharides-Based Chiral Stationary Phases. Separations, 9 (7), 157, 21 doi:10.3390/separations9070157.
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Pocrnić, M., Kontrec, D., Miljanić, S., Soldin, Ž., Budimir, A. & Galić, N. (2021) Gallium(III) complexes of aroylhydrazones derived from nicotinic acid hydrazide in solid state and in solution. Journal of molecular structure, 1227, 129564, 9 doi:10.1016/j.molstruc.2020.129564.
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Knežević, A., Dokli, I., Novak, J., Kontrec, D. & Lesac, A. (2021) Fluorinated twist-bend nematogens: the role of intermolecular interaction. Liquid crystals, 48 (5), 756-766 doi:10.1080/02678292.2020.1817585.
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Jurin, M., Kontrec, D., Dražić, T. & Roje, M. (2020) Enantioseparation of (±)-trans-β-lactam Ureas by Supercritical Fluid Chromatography. Croatica chemica acta, 93 (3), 203-213 doi:10.5562/cca3781.
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Kenđel, A., Miljanić, S., Kontrec, D., Soldin, Ž. & Galić, N. (2020) Copper(II) complexes of aroylhydrazones: preparation and structural characterization. Journal of molecular structure, 1207, 127783-127790 doi:10.1016/j.molstruc.2020.127783.
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Benković, T., Kontrec, D., Kazazić, S., Chiş, V., Miljanić, S. & Galić, N. (2020) Diverse coordination of aroylhydrazones toward iron(III) in solid state and in solution: spectrometric, spectroscopic and computational study. Molecular diversity, 24, 1253-1263 doi:10.1007/s11030-019-09989-6.
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Iliev, I., Kontrec, D., Detcheva, R., Georgieva, M., Balacheva, A., Galić, N. & Pajpanova, T. (2019) Cancer cell growth inhibition by aroylhydrazone derivatives. Biotechnology & biotechnological equipment, 33 (1), 756-763 doi:10.1080/13102818.2019.1608302.
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Polović, S., Ljoljić Bilić, V., Budimir, A., Kontrec, D., Galić, N. & Kosalec, I. (2019) Antimicrobial assesment of aroylhydrazone derivatives in vitro. Acta pharmaceutica, 69, 277-285 doi:10.2478/acph-2019-0020.
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Knežević, A., Sapunar, M., Buljan, A., Dokli, I., Hameršak, Z., Kontrec, D. & Lesac, A. (2018) Fine-tuning effect of p–p interactions on the stability of the NTB phase. Soft matter, 14, 8466-8474 doi:10.1039/c8sm01569d.
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Lesac, A., Baumeister, U., Dokli, I., Hameršak, Z., Ivšić, T., Kontrec, D., Viskić, M., Knežević, A. & Mandle, R. (2018) Geometric aspects influencing N-NTB transition - implication of intramolecular torsion. Liquid crystals, 45 (7), 1101-1110 doi:10.1080/02678292.2018.1453556.
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Benković, T., Kenđel, A., Parlov- Vuković, J., Kontrec, D., Chiş, V., Miljanić, S. & Galić, N. (2018) Multiple dynamics of aroylhydrazone induced by mutual effect of solvent and light - spectroscopic and computational study. Journal of molecular liquids, 255, 18-25 doi:10.1016/j.molliq.2018.01.158.
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Benković, T., Kenđel, A., Parlov- Vuković, J., Kontrec, D., Chiş, V., Miljanić, S. & Galić, N. (2018) Aromatic hydrazones derived from nicotinic acid hydrazide as fluorimetric pH sensing molecules: structural analysis by computational and spectroscopic methods in solid phase and in solution. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 190, 259-267 doi:10.1016/j.saa.2017.09.038.
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Benković, T., Kontrec, D., Tomišić, V., Budimir, A. & Galić, N. (2016) Acid-base Properties and Kinetics of Hydrolysis of Aroylhydrazones Derived from Nicotinic Acid Hydrazide. Journal of solution chemistry, 45 (8), 1227-1245 doi:10.1007/s10953-016-0504-8.
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Stražić, D., Benković, T., Gembarovski, D., Kontrec, D. & Galić, N. (2014) Comprehensive ESI MS and MS/MS analysis of aromatic hydrazones derived from nicotinic acid hydrazide. International journal of mass spectrometry, 371, 54-64 doi:10.1016/j.ijms.2014.07.036.
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Šumanovac Ramljak, T., Sohora, M., Antol, I., Kontrec, D., Basarić, N. & Mlinarić-Majerski, K. (2014) Memory of chirality in the phthalimide photocyclization of adamantane dipeptides. Tetrahedron letters, 55 (30), 4078-4081 doi:10.1016/j.tetlet.2014.05.118.
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Jurina, T., Terzić, S., Ahel, M., Stipičević, S., Kontrec, D., Kurtanjek, Ž. & Udiković-Kolić, N. (2014) Catabolism of terbuthylazine by mixed bacterial culture originating from s-triazine contaminated soil. Applied microbiology and biotechnology, 98 (16), 7223-7232 doi:10.1007/S00253-014-5774-8.
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Porobić, I., Kontrec, D. & Šoškić Milan (2013) Molecular recognition of indole derivatives by polymers imprinted with indole-3-acetic acid : A QSPR study. Bioorganic & medicinal chemistry, 21 (3), 653-659 doi:10.1016/j.bmc.2012.11.048.
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Galić, N., Brođanac, I., Kontrec, D. & Miljanić, S. (2013) Structural investigations of aroylhydrazones derived from nicotinic acid hydrazide in solid state and in solution. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 107, 263-270 doi:10.1016/j.saa.2013.01.028.
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Galić, N., Dijanošić, A., Kontrec, D. & Miljanić, S. (2012) Structural investigation of aroylhydrazones in dimethylsulphoxide/water mixtures. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 95, 347-353 doi:10.1016/j.saa.2012.03.086.
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Šunjić, V., Franić, D., Kontrec, D. & Roje, M. (2010) Recent Achievements in Simulated Moving Bed (SMB) Technology. Part II. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 59 (9), 439-450.
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Šunjić, V., Franić, D., Kontrec, D. & Roje, M. (2010) Recent Achievements in Simulated Moving Bed (SMB) Technology. Part I. Kemija u industriji : časopis kemičara i tehnologa Hrvatske, 59 (6), 283-294.
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Vinković, V., Roje, M., Kontrec, D. & Šunjić, V. (2008) Separation of BINAPO enantiomers on brush-type chiral stationary phases. ARKIVOC, (8), 242-253 doi:10.3998/ark.5550190.0009.819.
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Moslavac Forjan, D., Vinković, M., Kontrec, D., Lesac, A. & Vinković, V. (2007) NMR and HPLC study of chiral selectors with naphthyl unit. Structural chemistry, 18 (5), 585-591 doi:10.1007/s11224-007-9195-5.
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Moslavac Forjan, D., Vinković, V. & Kontrec, D. (2006) Performance of New HPLC Chiral Stationary Phase Derived from N-(3, 5-dinitrobenzoyl)-D-alpha-Phenylglycine with Quinoxaline Branching Unit. Acta chromatographica, 17, 97-107.
www.archiwum.us.edu.pl Landek, G., Vinković, M., Kontrec, D. & Vinković, V. (2006) Influence of Mobile Phase and Temperature on Separation of 1, 1’ -Binaphthyl-2, 2’ -Diol Enantiomers with Brush Type Chiral Stationary Phases Derived from L-Leucine. Chromatographia, 64 (7/8), 469-473.
Moslavac Forjan, D., Kontrec, D. & Vinković, V. (2006) Performance of Brush-Type HPLC Chiral Stationary Phases with Tertiary Amide in the Connecting Tether. Chirality, 18 (10), 857-869.
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Gazić, I., Kontrec, D., Lesac, A. & Vinković, V. (2005) The enantiomeric recognition of dihydropyrimidonic compounds by chiral selectors derived from from 4- or 2-chloro-3, 5-dinitrobenzoic acid. Tetrahedron: asymmetry, 16 (6), 1175-1182 doi:10.1016/j.tetasy.2005.01.042.
doi Zafirova, B., Landek, G., Kontrec, D., Šunjić, V. & Vinković, V. (2004) Study of Chromatographic Enantioseparation of the Esters of N-Dinitrobenzoyl (N-DNB) and N-Benzoyl (N-B) a-Amino Acids on Novel Chiral Stationary Phases Containing Structurally Matching N-DNB and N-B-a-AA Amides in the Chiral Selector. Croatica chemica acta, 77 (4), 573-579.
Kontrec, D., Vinković, V., Šepelj, M. & Šunjić, V. (2004) Eksperimenti i modeli u enantioprepoznavanju s kiralnim nepokretnim fazama Pirkleovog tipa koje sadrže aromatske pi-kisele ogranke. Croatica chemica acta, 77 (1-2), 31-51.
Kontrec, D., Vinković, V., Šunjić, V., Schuiki, B., Fabian, W. & Kappe, C. (2003) Enantioseparation of Racemic 4-Aryl-3, 4-dihydro-2(1H)-pyrimidones on Chiral Stationary Phases Based on 3, 5-Dimethylanilides of N-(4-Alkylamino-3, 5-dinitro)benzoyl L-α -Amino Acids. Chirality, 15 (6), 550-557.
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Ranogajec, A., Kontrec, D., Vinković, V. & Šunjić, V. (2003) Enantiomer separation and molecular recognition on new chiral stationary phases based on 4-chloro-3, 5-dinitrobenzoic acid amides of alfa, beta-aminoalcohols and alfa-arylethylamines. Journal of Liquid Chromatography & Related Technology, 26 (1), 63-83 doi:10.1081/JLC-120017153.
doi Abatangelo, A., Zanetti, F., Navarini, L., Kontrec, D., Vinković, V. & Šunjić, V. (2002) Enantiomerization of 3-Carbethoxy-1, 4-benzodiazepin-2-one ; Combined Chiral HPLC and Spectroscopic Study. Chirality, 14 (1), 12-17.
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Vinković, V., Kontrec, D., Šunjić, V., Navarini, L., Zanetti, F. & Azzolina, O. (2001) Mechanism of chiral recognition in the enantioseparation of 2-aryloxypropionic acids on new brush-type chiral stationary phases. Chirality, 13 (9), 581-587 doi:10.1002/chir.1181.
doi Kontrec, D., Abatangelo, A., Vinković, V. & Šunjić, V. (2001) Solid-phase Synthesis of Chiral Stationary Phases based on 2, 4, 5, 6-Tetrachloro-1, 3-dicyanobenzene Derivatives Spaced from N-3, 5-Dinitrobenzoyl alfa ; Amino Acids ; Comparative Study of Their Resolution Efficacy. Chirality, 13, 294-301.
Kontrec, D., Vinković, V., Lesac, A., Šunjić, V. & Aced, A. (2000) Novel chiral stationary phases comprising 2, 4-(or 2, 6)-diamino-5, 6-(or 2, 5)-dichlorobenzene-1, 3-dicarbonitrile and 1-acyl (1R, 2R)-diaminocyclohexane. Enantiomer, 5 (3-4), 333-344.
Novak, I., Kovač, B., Kontrec, D. & Šunjić, V. (2000) Electronic structure of persubstituted benzenes: caveats. Journal of electron spectroscopy and related phenomena, 109 (3), 281-286.
Kontrec, D., Vinković, V. & Šunjić, V. (2000) Preparation and Evaluation of the Chiral Stationary Phases Based on N-(-(2,5,6-Trichloro-1,3-dicyano)-phenyl Derivatives of L-a-Amino Acids. Journal of Liquid Chromatography & Related Technology, 23, 1203-1215.
Kontrec, D., Vinković, V. & Šunjić, V. (2000) Preparation and Evaluation of Stationary Phases Based on N, N-2,4- (or 4,6)-Disubstituted 4,5 (or 2,5)-dichloro-1,3-dicyanobenzenes. Chirality, 12, 63-70.
Kontrec, D., Vinković, V. & Šunjić, V. (1999) Stationary phases based on (R)-1-naphthylethylamine bound to 2,4,5,6-tetrachloro-1,3-dicyanobenzene. Chirality, 11 (9), 722-730.
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Kontrec, D., Vinković, V., Lesac, A., Šunjić, V. & Hollosi, M. (1999) Chiroptical and conformational properties of (R)-1-phenylethylamine derivatives of persubstituted benzene. Tetrahedron : asymmetry, 10 (10), 1935-1945 doi:10.1016/S0957-4166(99)00171-8.
doiwww.sciencedirect.com Turković, A., Zorc, H., Kontrec, D. & Vraneša, V. (1996) Comparative study of organo-metallic dyes and fullerenes in dye-sensitised TiO2 solar cells. Strojarstvo, 38 (6), 227-230.
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Hameršak, Z., Hollosi, M., Kontrec, D., Ladešić, B., Majer, Z. & Šunjić, V. (1995) Preparation and properties of glutathion conjugates of 2,4,5,6-tetrachloro-1,3-dicyanobenzene. Tetrahedron, 51 (8), 2331-2338 doi:10.1016/0040-4020(94)01090-M.
doi Kontrec, D., Ladešić, B., Hameršak, Z. & Šunjić, V. (1993) [14C] -UL-Chlorothalonil: a Study of the Catalytic Chlorination of [14C] -UL-1, 3-Dicyanobenzene. Applied radiation and isotopes, 44 (8), 1133-1137.
Patenti
Eurand (2004) Kiralne nepokretne faze za pripravu i odjeljivanje enantiomera, EP1091931.
Eurand (2004) Kiralne nepokretne faze temeljene na derivatima 4-amino-3, 5-dinitrobenzojeve kiseline, EP1370356.
Eurand (Mialno, Italija) (2004) Kiralne nepokretne faze za odjeljivanje enantiomera i njihovu pripravu, US 6, 437, 167 B1.
Kontrec, D., Vinković, V., Šunjić, V., Mariotti, P. & Navarini, L. (2003) Chiral stationary phases based on derivatives of 4.amino-3, 5-dinitrobenzoic acid, WO 02/070124 A1.
Šunjić, V., Kontrec, D. & Vinković, V. (2000) Chiral Stationary Phases for Enantiomers Separation and Their Preparation.
Šunjić, V., Kontrec, D. & Vinković Vladimir (2000) Chiral Stationary Phases for Enantiomers Separation and Their Preparation, PTC Pat. Prij..
Šunjić, V., Kontrec, D. & Vinković, V. (1998) Fasi stazionarie chirali per la separazione di enantiomeri e loro preparazione, IT. Pat. Prij..
Ruder Boskovic Institute New chiral stationary phases for chromatography based on aromatic allyl amines.
Chirallica d.o.o. Odjeljivanje enantiomera BINAPO-a SMB kromatografijom”,.
Ruđer Inovacije Nove kiralne nepokretne faze za kromatografiju temeljene na aromatskim alilnim aminima, P2080102A.
Chirallica, Zagreb Kiralni selektori zasnovani na 4- ili 2-metil-3, 5-dinitro benzojevoj kiselini.
Ocjenski radovi
Doktorske disertacije
Kontrec, D. (1999) 'Nove kiralne stacionarne faze za odjeljivanje enentiomera visokodjelotvornom tekućinskom kromatografijom', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.