2003. – 2006. dr. sc. bioloških znanosti

Ustanova: Prirodoslovno matematički fakultet, Sveučilište u Zagrebu, Hrvatska

1999. – 2003. mr. sc. bioloških znanosti

Ustanova: Prirodoslovno matematički fakultet, Sveučilište u Zagrebu, Hrvatska

Zaposlenje

2014. – danas – viša znanstvena suradnica

Ustanova: Zavod za molekularnu medicinu, Institut Ruđer Bošković, Zagreb

Prethodna zaposlenja

2008. – 2014. - znanstvena suradnica

Ustanova: Zavod za molekularnu medicinu, Institut Ruđer Bošković, Zagreb

1999. – 2008. - znanstvena novakinja

Ustanova: Zavod za molekularnu medicinu, Institut Ruđer Bošković, Zagreb

2019. Godišnja nagrada IRB-a za najbolji objavljeni znanstveni rad u 2018. godini

2017. Godišnja nagrada IRB-a za najbolji objavljeni znanstveni rad u 2016. godini

2000. Rektorova nagrada za rad “The link between met-enkephalin-induced down-regulation of APN activity and the release of superoxide anion.” Neuropeptides 34 (2); 121-128. T Marotti, T Balog, V Munić, S Sobočanec, M Abramić (2000).

• Sveučilište u Rijeci, Odjel za biotehnologiju, preddiplomski studij „Biotehnologija i istraživanje lijekova“
• Sveučilište u Zagrebu, Farmaceutsko-biokemijski fakultet, poslijediplomski doktorski studij "farmaceutsko-biokemisjke znanosti"

• Marija Pinterić, Iva I. Podgorski, Marijana Popović Hadžija, Ivana Tartaro Bujak, Ana Dekanić, Robert Bagarić, Vladimir Farkaš, Sandra Sobočanec* and Tihomir Balog. Role of Sirt3 in Differential Sex-Related Responses   to a High-Fat Diet in Mice (2020) Antioxidants 9;2; 174.
• Pinterić, Marija; Podgorski, Iva I.; Sobočanec Sandra^a,*; et al. De novo expression of transfected sirtuin 3 enhances susceptibility of human MCF-7 breast cancer cells to hyperoxia treatment. Free radical research, 52 (2018), 6; 672-684.
• Marina Musa, Matea Perić, Peter Bou Dib, Sobočanec Sandra, Ana Šarić, Anita Lovrić, Marina Rudan, Andrea Nikolić, Ira Milosević, Kristian Vlahoviček, Nuno Raimundo, Anita Kriško (2018) Heat-induced longevity in budding yeast requires respiratory metabolism and glutathione recycling. Aging-US, 10;9; 2407-2427.
• Bujak, Maro; Tartaro Bujak, Ivana; Sobočanec Sandra; Mihalj, Martina; Novak, Sanja; Ćosić, Anita; Tolušić Levak, Maja; Kopačin, Vjekoslav; Mihaljević, Branka; Balog, Tihomir et al. Trefoil Factor 3 Deficiency Affects Liver Lipid Metabolism. // Cellular physiology and biochemistry, 47 (2018), 2; 827-841 doi:10.1159/000490039 
• Marina Rudan, Peter Bou Dib, Marina Musa, Matea Kanunnikau, Sobočanec Sandra, David Rueda, Tobias Warnecke, Anita Kriško (2018) Normal mitochondrial function in Saccharomyces 1 cerevisiae has become dependent on inefficient splicing. eLife 7:e35330.
• Perić, Matea; Lovrić, Anita; Šarić, Ana; Musa, Marina; Bou Dib, Peter; Rudan, Marina; Nikolić, Andrea; Sobočanec Sandra; Mikecin, Ana-Matea; Dennerlein, Sven et al. TORC1-mediated sensing of chaperone activity alters glucose metabolism and extends lifespan. Aging Cell, 16 (2017), 5; 994-1005.
• Šarić, Ana; Crnolatac, Ivo; Bouillaud, Frédéric; Sobočanec Sandra*; Mikecin, Ana- Matea; Mačak Šafranko, Željka; Deligeorgiev, Todor; Piantanida, Ivo; Balog, Tihomir; Petit, Patrice Non-toxic fluorescent phosphonium probes to detect mitochondrial potential. Methods and Applications in Fluorescence, 5 (2017), 1; 015007-1 
• Sandra Sobočanec^a,*, Vedrana Filić, Mihaela Matovina, Dragomira Majhen, Željka Mačak Šafranko, Marijana Popović Hadžija, Željka Krsnik, Andrea Gudan Kurilj, Ana Šarić, Marija Abramić et al. (2016) Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo. Redox Biology, 8;149-159.
• Sandra Sobočanec^a,* Ana Šarić, Željka Mačak Šafranko, Marijana Popović Hadžija, Marija Abramić, Tihomir Balog (2015) The role of 17 Beta-estradiol in the regulation of antioxidant enzymes via the nrf2-keap1 pathway in livers of CBA/H mice. Life sciences, 130;57-65

Knjige i poglavlja u knjigama

Poglavlja u knjigama

• Sobočanec, S., Šarić, A., Korolija, M., Marjanović, M., Kralj, M., Knežević, J., Čretnik, M., Balog, T., Šverko, V., Kušić, B. & Marotti, T. (2008) Native propolis in vivo: On the oxidative/antioxidative effect and the mechanism of the action. U: Oršolić, N. & Bašić, I. (ur.) Scientific evidence of the Use of Propolis in Ethnomedicine. Kerala, India, Research SignPost, str. 121-131.

• Balog, T., Sobočanec, S., Šverko, V., Haberstock-Debić, H. & Marotti, T. (2006) Met-enkephalin in oxidative stress. U: Plotnikoff, N., Faith, R., Murgo, A. & Good, R. (ur.) Cytokines: Stress and Immunity. Boca Raton, London, New York, CRC Press Taylor and Francis Group, str. 143-157.

Radovi u časopisima

Znanstveni i pregledni radovi

• Košćak, M., Pehar, I., Božinović, K., Kumar Kole, G., Sobočanec, S., Podgorski, I., Pinterić, M., Müller-Buschbaum, K., Majhen, D., Piantanida, I. & Marder, T. (2022) Para-N-Methylpyridinium Pyrenes: Impact of Positive Charge on ds-DNA/RNA and Protein Recognition, Photo-Induced Bioactivity, and Intracellular Localisation. Pharmaceutics, 14 (11), 2499, 22 doi:10.3390/pharmaceutics14112499.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Matić, S., Tomašić Paić, A., Sobočanec, S., Pinterić, M., Pipalović, G., Martinčić, M., Matovina, M. & Tomić, S. (2022) Interdisciplinary study of the effects of dipeptidyl-peptidase III cancer mutations on the KEAP1-NRF2 signaling pathway. International journal of molecular sciences, 23 (4), 1994, 15 doi:10.3390/ijms23041994.

  doiwww.mdpi.comwww.ncbi.nlm.nih.govfulir.irb.hr

• Dominko, K., Rastija, A., Sobočanec, S., Vidatić, L., Meglaj, S., Lovinčić Babić, A., Hutter-Paier, B., Colombo, Alessio-Vittorio, , Lichtenthaler, S., Tahirović, S. & Hećimović, S. (2021) Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation. International journal of molecular sciences, 22 (24), 13256, 27 doi:10.3390/ijms222413256.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Pinterić, M., Podgorski, I., Popović Hadžija, M., Tartaro Bujak, I., Tadijan, A., Balog, T. & Sobočanec, S. (2021) Chronic High Fat Diet Intake Impairs Hepatic Metabolic Parameters in Ovariectomized Sirt3 KO Mice. International journal of molecular sciences, 22 (8), 4277, 17 doi:10.3390/ijms22084277.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Podgorski, I., Pinterić, M., Marčinko, D., Popović Hadžija, M., Filić, V., Ciganek, I., Pleše, D., Balog, T. & Sobočanec, S. (2020) Combination of sirtuin 3 and hyperoxia diminishes tumorigenic properties of MDA-MB-231 cells. Life sciences, 254, 117812, 13 doi:10.1016/j.lfs.2020.117812.

  doi

• Pinterić, M., Podgorski, I., Popović- Hadžija, M., Filić, V., Paradžik, M., Proust, B., Dekanić, A., Ciganek, I., Pleše, D., Marčinko, D., Balog, T. & Sobočanec, S. (2020) Sirt3 Exerts Its Tumor-Suppressive Role by Increasing p53 and Attenuating Response to Estrogen in MCF-7 Cells. Antioxidants, 9 (4), 294, 21 doi:10.3390/antiox9040294.

  doiwww.mdpi.comfulir.irb.hr

• Pinterić, M., Podgorski, I., Popović Hadžija , M., Tartaro Bujak, I., Dekanić, A., Bagarić, R., Farkaš, V., Sobočanec, S. & Balog, T. (2020) Role of Sirt3 in Differential Sex-Related Responses to a High-Fat Diet in Mice. Antioxidants, 9 (2), 174, 19 doi:10.3390/antiox9020174.

  doiwww.mdpi.comdoi.orgfulir.irb.hr

• Musa, M., Perić, M., Bou Dib, P., Sobočanec, S., Šarić, A., Lovrić, A., Rudan, M., Nikolić, A., Milošević, I., Vlahoviček, K., Raimundo, N. & Kriško, A. (2018) Heat-induced longevity in budding yeast requires respiratory metabolism and glutathione recycling. Aging-US, 10, 2407-2427 doi:10.18632/aging.101560.

  doiwww.aging-us.comfulir.irb.hr

• Bujak, M., Tartaro Bujak, I., Sobočanec, S., Mihalj, M., Novak, S., Ćosić, A., Tolušić Levak, M., Kopačin, V., Mihaljević, B., Balog, T., Drenjančević, I. & Baus Lončar, M. (2018) Trefoil Factor 3 Deficiency Affects Liver Lipid Metabolism. Cellular physiology and biochemistry, 47 (2), 827-841 doi:10.1159/000490039.

  doiwww.karger.comfulir.irb.hr

• Pinterić, M., Podgorski, I., Sobočanec, S., Popović Hadžija, M., Paradžik, M., Dekanić, A., Marinović, M., Halasz, M., Belužić, R., Davidović, G., Ambriović Ristov, A. & Balog, T. (2018) De novo expression of transfected sirtuin 3 enhances susceptibility of human MCF-7 breast cancer cells to hyperoxia treatment. Free radical research, 52 (6), 672, 684 doi:10.1080/10715762.2018.1462495.

  doiwww.tandfonline.com

• Perović, A., Sobočanec, S., Dabelić, S., Balog, T. & Dumić, J. (2018) Effect of scuba diving on the oxidant / antioxidant status, SIRT1 and SIRT3 expression in recreational divers after a winter non-dive period. Free radical research, 52 (2), 188-197 doi:10.1080/10715762.2017.1422211.

  doi

• Perović, A., Nikolac, N., Bratičević Njire, M., Milčić, A., Sobočanec, S., Balog, T., Dabelić, S. & Dumić, J. (2017) Does recreational scuba diving have clinically significant effect on routine haematological parameters?. Biochemia medica, 27 (2), 325-331 doi:10.11613/BM.2017.035.

  doihrcak.srce.hr

• Perić, M., Lovrić, A., Šarić, A., Musa, M., Bou Dib, P., Rudan, M., Nikolić, A., Sobočanec, S., Mikecin, A., Dennerlein, S., Milošević, I., Vlahoviček, K., Raimundo, N. & Kriško, A. (2017) TORC1-mediated sensing of chaperone activity alters glucose metabolism and extends lifespan.. Aging cell, 16 (5), 994-1005 doi:10.1111/acel.12623.

  doi

• Šarić, A., Crnolatac, I., Bouillaud, F., Sobocanec, S., Mikecin, A., Mačak Šafranko, Ž., Deligeorgiev, T., Piantanida, I., Balog, T. & Petit, P. (2017) Non-toxic fluorescent phosphonium probes to detect mitochondrial potential. Methods and applications in fluorescence, 5 (1), 015007, 13 doi:10.1088/2050-6120/aa5e64.

  doi

• Mačak Šafranko, Ž., Balog, T., Musa, M., Tartaro Bujak, I. & Sobočanec, S. (2016) The effect of 17β-estradiol on sex-dimorphic cytochrome P450 expression patterns induced by hyperoxia in the liver of male CBA/H mice. Molecular and cellular biochemistry, 421 (1/2), 183-191 doi:10.1007/s11010-016-2802-2.

  doi

• Sobočanec, S., Filić, V., Matovina, M., Majhen, D., Šafranko, Ž., Popović Hadžija, M., Krsnik, Ž., Gudan Kurilj, A., Šarić, A., Abramić, M. & Balog, T. (2016) Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo. Redox Biology, 8, 149-159 doi:10.1016/j.redox.2016.01.003.

  doi

• Sobočanec, S., Mačak Šafranko, Ž., Šarić, A., Korolija, M., Popović Hadžija, M. & Balog, T. (2016) Response to hyperoxia is associated with similar ho-1 gene expression level in lungs of aging CBA mice of both sexes. Biochemistry and biophysics reports, 5, 55-62 doi:10.1016/j.bbrep.2015.09.002.

  doiwww.sciencedirect.com

• Šarić, A., Sobočanec, S., Mačak Šafranko, Ž., Popović Hadžija, M., Bagarić, R., Farkaš, V., Švarc, A., Marotti, T. & Balog, T. (2015) Diminished resistance to hyperoxia in brains of reproductively senescent female CBA/H mice. Medical science monitor basic research, 21, 191-199 doi:10.12659/MSMBR.895356.

  doibasic.medscimonit.comfulir.irb.hr

• Sobočanec, S., Šarić, A., Mačak Šafranko, Ž., Popović Hadžija, M., Abramić, M. & Balog, T. (2015) The role of 17 Beta-estradiol in the regulation of antioxidant enzymes via the nrf2-keap1 pathway in livers of CBA/H mice. Life sciences, 130, 57-65 doi:10.1016/j.lfs.2015.03.014.

  doi

• Mačak Šafranko, Ž., Sobočanec, S., Šarić, A., Jajčanin Jozić, N., Krsnik, Ž., Aralica, G., Balog, T. & Abramić, M. (2015) The effect of 17β-estradiol on the expression of dipeptidyl peptidase III and heme oxygenase 1 in liver of CBA/H mice. Journal of endocrinological investigation, 38 (4), 471-479 doi:10.1007/s40618-014-0217-z.

  doi

• Šarić, A., Sobočanec, S., Mačak-Šafranko, Ž., Popović-Hadžija, M., Aralica, G., Korolija, M., Kušić, B. & Balog, T. (2014) Female headstart in resistance to hyperoxia-induced oxidative stress. Acta biochimica Polonica, 61 (4), 801-807.

• Šverko, A., Sobočanec, S., Kušić, B., Mačak-Šafranko, Ž., Šarić, A., Leniček, T., Kraus, O., Andrišić, L., Korolija, M., Balog, T., Borović, S. & Marotti, M. (2011) Superoxide dismutase and cytochrome P450 isoenzymes might be associated with higher risk of renal cell carcinoma in male patients. International immunopharmacology, 11 (6), 639-645 doi:10.1016/j.intimp.2010.12.023.

  doi

• Mačak-Šafranko, Ž., Sobočanec, S., Šarić, A., Balog, T., Šverko, V., Kušić, B. & Marotti, T. (2011) Cytochrome P450 gender-related differences in response to hyperoxia in young CBA mice. Experimental and toxicologic pathology, 63 (4), 345-350 doi:10.1016/j.etp.2010.02.009.

  doi

• Sobočanec, S., Balog, T., Šariċ, A., Mačak-Šafranko, Ž., Štroser, M., Žarković, K., Žarković, N., Stojković, R., Ivanković, S. & Marotti, T. (2011) Antitumor effect of Croatian propolis as a consequence of diverse sex-related dihydropyrimidine dehydrogenase (DPD) protein expression. Phytomedicine, 18, 852-858 doi:10.1016/j.phymed.2011.01.015.

  doi

• Sobočanec, S., Balog, T., Šarić, A., Šverko, V., Žarković, N., Čipak Gašparović, A., Žarković, K., Waeg, G., Mačak Šafranko, Ž., Kušić, B. & Marotti, T. (2010) Cyp 4a14 overexpression induced by hyperoxia in female CBA mice as a possible contributor of increased resistance to oxidative stress. Free radical research, 44 (2), 181-190 doi:10.3109/10715760903390820.

  doi

• Balog, T., Šarić, A., Sobočanec, S., Kušić, B. & Marotti, T. (2010) Endomorphine-suppressed nitric oxide release from mice peritoneal macrophages. Neuropeptides, 44 (1), 25-29 doi:10.1016.

  doi

• Šarić, A., Sobočanec, S., Balog, T., Kušić, B., Šverko, V., Dragović-Uzelac, V., Levaj, B., Čosić, Z., Mačak Šafranko, Ž. & Marotti, T. (2009) Improved antioxidant and anti-inflamatory potential in mice consuming sour cherry juice (Prunus Cerasus cv. Maraska). Plant foods for human nutrition, 64 (4), 231-237 doi:10.1007/s11130-009-0135-y.

  doi

• Šarić, A., Balog, T., Sobočanec, S., Kušić, B., Šverko, V., Rusak, G., Likić, S., Bubalo, D., Pinto, B., Reali, D. & Marotti, T. (2009) Antioxidant effects of flavonoid from Croatian Cystus incanus L. rich bee pollen. Food and Chemical Toxicology, 47 (3), 547-554 doi:10.1016/j.fct.2008.12.007.

  doi

• Sobočanec, S., Balog, T., Kušić, B., Šverko, V., Šarić, A. & Marotti, T. (2008) Differential response to lipid peroxidation in male and female mice with age: correlation of antioxidant enzymes matters. Biogerontology, 9 (5), 335-343.

• Šarić, A., Balog, T., Sobočanec, S. & Marotti, T. (2007) Endomorphin 1 activates NOS2 activity and downregulates NOS2 mRNA expression. Neuroscience, 144 (4), 1454-1461. (https://www.bib.irb.hr/286856).

• Jasprica, I., Mornar, A., Debeljak, Ž., Smolčić-Bubalo, A., Medić-Šarić, M., Mayer, L., Romić, Ž., Bućan, K., Balog, T., Sobočanec, S. & Višnja, Š. (2007) In vivo study of propolis supplementation effects on antioxidative status and red blood cells. Journal of Ethnopharmacology, 110 (3), 548-554.

• Sobočanec, S., Šverko, V., Balog, T., Šarić, A., Rusak, G., Likić, S., Kušić, B., Katalinić, V., Radić, S. & Marotti, T. (2006) Oxidant/Antioxidant Properties of Croatian Native Propolis. Journal of Agricultural and Food Chemistry, 54 (21), 8018-8026.

• Sobočanec, S., Kušić, B., Šverko, V., Balog, T. & Marotti, T. (2006) Methionine-enkephalin modulated regulation of oxidant/antioxidant status in liver of CBA mice. Biogerontology (Dordrecht), 7, 53-62.

• Balog, T., Sobočanec, S., Šverko, V., Krolo, I., Ročić, B., Marotti, M. & Marotti, T. (2006) The influence of season on oxidant-antioxidant status in trained and sedentary subjects. Life Sciences, 78 (13), 1441-1447.

• Šverko, A., Sobočanec, S., Balog, T., Kušić, B., Šverko, V. & Marotti, T. (2005) Does long-term exercise modulate oxidant/antioxidant status in humans? Comparison between lipid peroxidation and catalase activity in fresh and stored samples. Croatica Chemica Acta, 78 (3), 361-366.

• Sobočanec, S., Balog, T., Šverko, V. & Marotti, T. (2005) Met-enkephalin modulation of age-related changes in red cell antioxidant status. Physiological Research, 54, 97-104.

• Balog, T., Sobočanec, S., Šverko, V. & Marotti, T. (2004) Met-enkephalin modulates resistance to oxidative stress in mouse brain. Neuropeptides, 38 (5), 298-303.

• Šverko, V., Sobočanec, S., Balog, T. & Marotti, T. (2004) Age and gender differences in antioxidant enzyme activity : potential relationship to liver carcinogenesis in male mice. Biogerontology, 5, 235-242.

• Šverko, V., Sobočanec, S., Balog, T., Čolić, M. & Marotti, T. (2004) Natural micronized clinoptilolite and clinoptilolite mixtures with 40% Urtica dionica L. exstract as possible antioxidants. Food Technology and Biotechnology, 42 (3), 189-192.

• Sobočanec, S., Balog, T., Šverko, V. & Marotti, T. (2003) Sex-dependent antioxidant enzyme activities and lipid peroxidation in ageing mouse brain. Free radical research, 37 (7), 743-748.

• Šverko, V., Balog, T., Sobočanec, S., Gavella, M. & Marotti, T. (2002) Age-associated alteration of lipid peroxidation and superoxide dismutase activity in CBA and AKR mice. Experimental gerontology, 37, 1031-1039.

• Šverko, V., Sobočanec, S., Balog, T. & Marotti, T. (2002) Met-enkephalin modulates lipid peroxidation and total sialic acid level in CBA mice in age- and sex-dependent manners. Experimental gerontology, 37, 1413-1421.

• Balog, T., Marotti, T., Abramić, M., Svoboda-Beusan, I., Sobočanec, S. & Hršak, I. (2001) Neutrophil neutral endopeptidase variation and its regulation by opioid peptides. International Immunopharmacology, 1 (3), 569-579.

• Šverko, V., Balog, T., Gavella, M., Lipovac, V., Marotti, T. & Sobočanec, S. (2001) Oxidant/antioxidant status in AKR mice. Periodicum biologorum, 103 (1), 3-9.

• Balog, T., Marotti, T., Musani, V., Sobočanec, S. & Šverko, V. (2001) The effect of methionine enkephalin on nitric oxide release in mice is age and gender related. Pharmacological research, 44 (4), 287-292 doi:10.1006/phrs.2001.0866.

  doi

• Marotti, T., Balog, T., Munić, V., Sobočanec, S. & Abramić, M. (2000) The link between met-enkephalin-induced down-regulation of APN activity and release of superoxide anion. Neuropeptides, 34 (2), 121-128 doi:10.1054/npep.2000.0801.

  doi

Ocjenski radovi

Doktorske disertacije

• Sobočanec, S. (2006) 'Učinak propolisa na oksidacijski/antioksidacijski status CBA miša', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb.

• Sobočanec, S. (2006) 'Utjecaj propolisa na oksidacisjki/antioksidacijski status u CBA miša', doktorska disertacija, Prirodoslovno-matematički fakultet, Zagreb. (https://www.bib.irb.hr/286858).

Magistarski radovi

• Sobočanec, S. (2003) 'Oksidacijski/antioksidacijski status u CBA miševa različite dobi', magistarski rad, Prirodoslovno-matematički fakultet, Zagreb.

članica Hrvatskog imunološkog društva (HID)

članica HNE-Cluba (član International Society for Free Radicals Research-a)

članica Hrvatskog društva za biokemiju i molekularnu biologiju (član FEBS-a)

članica Hrvatskog društva za istraživanje raka (HDIR)