- Osnovna i srednja škola (Gimnazija M.A. Reljković) završena u Vinkovcima, maturirao 1987. god.;

- 1994. god. diplomirao biologiju, smjer dipl. inž. biologije-ekologije na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu;

- 1998. god. magisterij iz prirodnih znanosti, polje biologija, grana toksikologija, na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu;

- 1999. god. doktorat iz prirodnih znanosti, polje biologija, grana ekotoksikologija, na Prirodoslovno-matematičkom fakultetu Sveučilišta u Zagrebu.

Aktualni projekti:

-      Ecotoxicological characterization of biologically active substances and complex marine environment samples – Project within the Centre for Excellence for Science and Technology – Integration of Mediterranean Region (ZCI-STIM;  https://stim.unist.hr/hr/) (2017-2021) – leading institution University of Split, other partners Ruđer Bošković Institute, Zagreb (IRB) and Mediteranean Institute for Life Sciences (MEDILS); principal investigator.

-      Understanding the (eco)toxicological role of selected SLC and MATE transport proteins in zebrafish (Danio rerio) using functional genomics tools, (2020-2023) – Croatian Science Foundation research project – principal investigator;

-        M. Erk, T. Smital – Kolegij Biološki učinci metala i organskih zagađivala na morske organizme; Doktorski studij iz Oceanologije, Prirodoslovno-matematički fakultet, Sveučilište u Zagrebu;

-        T. Smital – Kolegij Ekotoksikologija; Doktorski studij “Zaštita prirode i okoliša”, Sveučilište u Osijeku;

-        G. Klobučar, M. Pavlica, V. Garaj-Vrhovac, T. Smital – Kolegij Biomarkeri u biomonitoringu zagađenja okoliša; Doktorski studij iz Biologije, Prirodoslovno-matematički fakultet, Sveučilište u Zagrebu

SCI publikacije

1. Smital T, Pivčević B. and Kurelec B. (1996) Reversal of multidrug resistance by extract from the marine alga Caulerpa taxifolia. Period. Biol., 98: 165-171.
2. Smital T. and Kurelec B. (1997) Inhibitors of the multixenobiotic resistance mechanism in natural waters: In vivo demonstration of their effects. Environ. Toxicol. Chem. 16: 2164-2170.
3. Kurelec B., Smital T., Britvić S., Pivčević B., Krča S., Jelaska D., Balen S., Sauerborn R. and Mustajbegović S. (1997) Multixenobiotic defence mechanism in aquatic organisms. Period. Biol. 99: 319-328.
4. Smital. T. and Kurelec B. (1998) The chemosensitizers of multixenobiotic resistance mechanism in aquatic invertebrates; A new class of pollutants. Mutat. Res.-Fund. Mol. M. 399: 45-53.
5. Kurelec B., Britvić S. and Smital T. (1998) Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment. Mar. Environ. Res. 46: 415-419.
6. Smital T. and Kurelec B. (1998) The activity of multixenobiotic resistance mechanism determined by rhodamine B - efflux method as a biomarker of exposure. Mar. Environ. Res. 46: 443-447.
7. Osmak M., Brozović A., Ambriović-Ristov A., Hadžija M., Pivčević B., and Smital T. (1998) Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells. Neoplasma 45: 223-230.
8. Kurelec, B., Smital, T., Pivčević, B., Eufemia, N. and Epel, D. (2000) Multixenobiotic resistance, P-glycoprotein, and chemosensitizers. Ecotoxicology 9: 307-327.
9. Smital, T., Sauerborn, R., Pivčević, B., Krča, S. and Kurelec, B. (2000) Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates, Comp. Biochem. Physiol C., 126: 175-186.
10. Ramljak, S., Hackenberger, B.K., Smital, T. and Britvić, S. (2000) Evaluation of the genotoxic and cytochrome P450 monooxygenase-inhibitory potential of dicuran on procariotic and eucaryotic test systems, J.  Environ. Sci. Health B. B35: 751-770.
11. Smital, T. and Sauerborn, R. (2002) Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio. Mar. Environ. Res. 54: 449-453.
12. Smital, T., Sauerborn, R. and Hackenberger, B.K. (2003) Inducibility of the P-glycoprotein transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha. Aquat. Toxicol. 65: 443-465.
13. Sauerborn, R., Stupin Polancec, D., Zaja, R. and Smital, T. (2004) Identification of the multidrug resistance-associated protein (MRP) related gene in the red mullet (Mullus barbatus). Mar. Environ. Res., 58: 199-204.
14. Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A.M., Vega, R.L. and Epel, D. (2004) Emerging contaminants – pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms. Mut. Res.-Fund. Mol. M., 552: 101-117.
15. Žaja, R., Klobučar, G.I.V., Sauerborn Klobučar, R., Hackenberger, B., and Smital, T. (2006) Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves. Comp. Biochem. Physiol. C., 143: 103-112.
16. Žaja, R., Sauerborn Klobučar R. and Smital, T. (2007) Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line. Aquat. Toxicol., 81: 365-376.
17. Krča, S., Žaja, R., Čalić, V., Terzić, S., Grubešić, M.S., Ahel, M. and Smital, T. (2007) Hepatic biomarker responses to organic contaminants in feral chub (Leuciscus cephalus) – laboratory characterization and field study in the Sava River, Croatia. Environ. Toxicol. Chem., 26: 2620-2633.
18. Žaja, R., Caminada, D., Lončar, J., Fent, K. and Smital, T. (2008) Development and characterization of P-glycoprotein 1 (Pgp1; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line. Toxicol. Appl. Pharmacol., 227: 207-218.
19. Žaja, R., Munić, V., and Smital, T. (2008) Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes. Mar. Environ. Res., 66: 77-79.
20. Källqvist, T., Milačič, R., Smital, T., Thomas, K.V., Vranes, S. and Tollefsen, K-E. (2008) Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata. Water Res., 42: 2146-2156.
21. Epel, D., Stevenson, C.N., MacManus-Spencer, L.A., Luckenbach, T., Hamdoun, A., and Smital, T. (2008) Efflux transporters: newly appreciated roles in protection against pollutants. Environ. Sci. Tech., 42: 3914-3920.
22. Traven, L., Žaja, R., Lončar, J., Smital, T. and Mićović, V. (2008) CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line. Toxicol. In Vitro, 22: 1648-1656.
23. Caminada, D., Žaja, R., Smital, T. and Fent, K. (2008) Human pharmaceuticals modulate P-gp1 (ABCB1) transport activity in the fish cell line PLHC-1. Aquat. Toxicol., 90: 214–222.
24. Žaja, R., Munić, V., Sauerborn Klobučar, R., Ambriović-Ristov, A., Smital, T. (2008) Cloning and functional characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol. 90: 322-332.
25. Bošnjak, I., Heim, W., Smital, T., Epel, D., Coale, K., Franekić-Čolić, J., Hamdoun, A. (2009) Multidrug resistance associated protein transport activity mediates differences in accumulation and toxicity of inorganic and organic mercury in sea urchin embryos. Environ. Sci. Tech. 43: 8374-8380.
26. Lončar, J., Popović, M., Žaja, R., Smital, T. (2010) Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. C. 151: 209-215.
27. Popović, M., Žaja, R., Lončar, J., Smital, T. (2010) A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1. Mar. Environ. Res. 69: S11-S13.
28. Popović, M., Žaja, R., Smital, T. (2010) Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution. Comp. Biochem. Physiol. A 155: 327-335. 
29. Bošnjak, I., Šegvić, T., Smital, T., Franekić, J., Mladineo, I. (2011) Sea Urchin Embryotoxicity Test for Environmental Contaminants—Potential Role of the MRP Proteins. Water Air Soil Poll. 217: 627-636.
30. Fischer, S., Loncar, J., Zaja, R., Schnelle, S., Schirmer, K., Smital, T., Luckenbach, T. (2011) Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 101: 438-446.
31. Smital, T., Terzic, S., Zaja, R., Senta, I., Pivcevic, B., Popovic, M., Mikac, I., Tollefsen, K.E., Thomas, K.V., Ahel, M. (2011) Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays. Ecotoxicol. Environ. Saf. 74: 844-851.
32. Sauerborn Klobučar, R., Zaja, R., Franjević, D., Brozović, A., Smital, T. (2011) Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish. Arh. Hig. Rada Toksikol. 61: 175-181.
33. Zaja, R., Loncar, J., Popovic, M., Smital, T. (2011) First characterization of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line. Aquat. Toxicol. 103: 53-62.
34. Reifferscheid, G., Maes, H., Allner, B., Badurova, J., Belkin, S., Blum, K., Brauer, F., Bressling, J., Domeneghetti, S., Elad, T., Flückiger-Isler, S., Grummt, H.J., Guertler, R., Hecht, A., Heringa, M., Hollert, H., Huber, S., Kramer, M., Magdeburg, A., Ratte, T., Sauerborn-Klobucar, R., Sokolowski, A., Soldan, P., Smital, T., Stalter, D., Venier, P., Ziemann, C., Zipperle, J., Buchinger, S. (2012) International round-robin study on the Ames fluctuation test. Environ. Mol. Mutag. 53: 185-197.
35. Della Torre, C., Zaja, R., Loncar, J., Smital, T., Focardi, S., Corsi, I. (2012) Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line. Chem. Biol. Interac. 198: 9-17.
36. Smital, T., Terzić, S., Lončar, J., Senta, I., Zaja, R., Popović, M., Mikac, I., Tollefsen, K-E., Thomas, K.V., Ahel, M. (2013) Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays. Environ. Sci. Poll. Res. 20: 1384-1395.
37. Zaja, R., Terzić, S., Senta, I., Lončar, J., Popović, M., Ahel, M., Smital, T. (2013) Identification of P-glycoprotein (P-gp, Abcb1) inhibitors in contaminated freshwater sediments. Environ. Sci. Tech. 47: 4813-4821.
38. Traven, L., Mićović, V., Vukić Lušić, D., Smital, T. (2013) The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environmental risk assessment. Environ Monit Assess. 185: 9009-9018.
39. Bošnjak, I., Zaja, R., Klobučar, R.S., Sver, L., Franekić, J., Smital, T. (2013) Identification of ABC Transporter Genes in Gonad Tissue of Two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. Bull. Environ. Contam. Toxicol. 91: 415-419. 
40. Popovic, M., Zaja, R., Fent, K., Smital, T. (2013) Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide. J. Biol. Chem. 288: 33894–33911.
41. Ferreira, M., Santos, P., Rey-Salgueiro, L., Zaja, R., Reis-Henriques, M.A., Smital, T. (2014) The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European seabass (Dicentrarchus labrax) primary hepatocytes. Chemosphere 100: 152-159.
42. Popovic, M., Zaja, R., Fent, K., Smital, T. (2014) Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1). Toxicol. Appl. Pharmacol. 280: 149-158.
43. Glisic, B., Mihaljevic, I., Popovic, M., Zaja, R., Loncar, J., Fent, K., Kovacevic, R., Smital, T. (2015) Characterization of glutathione-S-transferases in zebrafish (Danio rerio). Aquat. Toxicol. 158: 50-62.
44. Lončar, J., Popović, M., Krznar, P., Zaja, R., Smital, T. (2016) The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio). Sci. Rep. 6: 28937, DOI: 10.1038/srep28937.  
45. Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2016) Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio). BMC Genomics, 17: 626, DOI 10.1186/s12864-016-2981-y.
46. Zaja, R., Popović, M., Lončar, J., Smital, T. (2016) Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter. Comp. Biochem. Physiol. C, 190, 15-23.
47. Mihaljević, I., Popović, M., Žaja, R., Maraković, N., Šinko, G., Smital, T. (2017) Interaction between the zebrafish (Danio rerio) organic cation transporter 1 (Oct1) and endo- and xenobiotics. Aquat. Toxicol. 187: 18-28.
48. Marić, P., Ahel, M., Senta, I., Terzić, S., Mikac, I, Žuljević, A., Smital, T. (2017) Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia. Chemosphere 174: 643-654.
49. Dragojević, J., Mihaljević, I., Popović, M., Zaja, R., Smital, T. (2017) In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e. Toxicol In Vitro 46: 246-256.
50. Terzić, S., Udikovic-Kolić, N., Jurina, T., Krizman-Matašica, I., Senta, I., Mihaljević, I., Lončar, J., Smital, T., Ahel, M. (2018) Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation. J. Haz. Mat. 349: 143-152.
51. Lončar, J., Smital, T. (2018) Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 7 (Mate7/Slc47a7). Aquat. Toxicol. 205: 193-203.
52. Dean Karaica, Davorka Breljak, Jovica Lončar, Mila Lovrić, Vedran Micek, Ivana Vrhovac Madunić, Hrvoje Brzica, Carol M. Herak-Kramberger, Jana Ivković Dupor, Marija Ljubojević, Tvrtko Smital, Željka Vogrinc, Gerhard Burckhardt, Birgitta C. Burckhardt, Ivan Sabolić (2018) Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys. Arh. Hig. Rada Toksikol. 69: 286-303
53. Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Biodegradation study of methadone by adapted activated sludge: elimination kinetics, transformation products and ecotoxicological evaluation. Chemosphere 214: 719-728.
54. Bašica, B., Mihaljević, I., Maraković, N., Kovačević, R., Smital, T. (2019) Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class. Aquat. Toxicol. 208: 196-207.
55. Kostanjevecki, P., Petric, I., Loncar, J., Smital, T., Ahel, M., Terzic, S. (2019) Aerobic biodegradation of tramadol by pre-adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment. Sci. Total. Environ. 687: 858-866.
56. Dragojević, J., Mihaljević, I., Popović, M., Smital, T. (2019) Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds. Comp. Biochem. Physiol. B 236: 110309
57. Mihaljević, I., Bašica, B., Maraković, N., Kovačević, R., Smital, T. (2020) Interaction of organotin compounds with three major glutathione S-transferases in zebrafish. Toxicol. In Vitro 62: 104713.
58. Dragojević, J., Marić, P., Lončar, J., Popović, M., Mihaljević, I., Smital, T. (2020) Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3. Comp. Biochem. Physiol. C 231: 108742
59. Marić, P., Ahel, M., Babić, O., Simeunović, J., Smital, T. (2020) Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis. Ecotoxicology 10.1007/s10646-020-02201-8

Izvorni znanstveni rad

• Smital, Tvrtko ; Ahel, Marijan | Ecotoxicological characterization of the Sava River – biomarker responses and biological assays // The Sava River. | Berlin : Heidelberg: Springer, 2015. str. 177-200

  link.springer.com

• Smital, Tvrtko | Acute and Chronic Effects of Emerging Contaminants // Emerging Contaminants from Industrial and Municipal Waste - Occurrence, Analysis and Effects. | Berlin: Springer, 2008. str. 154-193 . doi: 10.1007/978-3-540-74795-6_3

  doilink.springer.comdoi.org

• Epel, David ; Smital, Tvrtko | Multidrug-multixenobiotic transporters and their significance with respect to environmental levels of pharmaceuticals and personal care products // Pharmaceuticals and personal care products in the environment - scientific and regulatory issues. | Washington (MD): American Chemical Society (ACS) ; Oxford University Press, 2001. str. 244-263-x

Izvorni znanstveni rad

• Frleta, Roberta ; Popović, Marijana ; Smital, Tvrtko ; Šimat, Vida | Comparison of Growth and Chemical Profile of Diatom Skeletonema grevillei in Bioreactor and Incubation-Shaking Cabinet in Two Growth Phases // Marine drugs, 20 (2022), 11; 697, 16. doi: 10.3390/md20110697

  doifulir.irb.hrwww.mdpi.com

• Marić, Petra; Ahel, Marijan; Maraković, Nikola; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Selective interaction of microcystin congeners with zebrafish (Danio rerio) Oatp1d1 transporter // Chemosphere, 283 (2021), 131155, 12. doi: 10.1016/j.chemosphere.2021.131155

  doiwww.sciencedirect.comfulir.irb.hr

• Dragojević, Jelena ; Marakovic, Nikola ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oatp2b1 as a functional ortholog of the human OATP2B1 transporter // Fish physiology and biochemistry, 47 (2021), 6; 1837-1849. doi: 10.1007/s10695-021-01015-7

  doiwww.scopus.com

• Dragojević, Jelena ; Marić, Petra ; Lončar, Jovica ; Popović, Marta ; Mihaljević, Ivan ; Smital, Tvrtko | Environmental contaminants modulate transport activity of zebrafish organic anion transporters Oat1 and Oat3 // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 231 (2020), 108742, 8. doi: 10.1016/j.cbpc.2020.108742

  doiwww.sciencedirect.comdoi.org

• Mihaljević, Ivan ; Bašica, Branka ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Interaction of organotin compounds with three major glutathione S-transferases in zebrafish // Toxicology in vitro, 62 (2020), 104713, 9. doi: 10.1016/j.tiv.2019.104713

  doiwww.sciencedirect.comdoi.org

• Marić, Petra ; Ahel, Marijan ; Babić, Olivera ; Simeunović, Jelica ; Smital, Tvrtko | Ecotoxicological profiling of selected cyanobacterial strains using multi-endpoint effect-directed analysis // Ecotoxicology, 2020 (2020), s10646-020-02201-8, 16. doi: 10.1007/s10646-020-02201-8

  doidoi.orglink.springer.comlink.springer.com

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Smital, Tvrtko | Zebrafish (Danio rerio) Oat1 and Oat3 transporters and their interaction with physiological compounds // Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 236 (2019), 110309, 11. doi: 10.1016/j.cbpb.2019.110309

  doiwww.sciencedirect.comdoi.org

• Kostanjevečki, Petra ; Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Aerobic biodegradation of tramadol by pre- adapted activated sludge culture: Cometabolic transformations and bacterial community changes during enrichment // Science of the total environment, 687 (2019), 858-866. doi: 10.1016/j.scitotenv.2019.06.118

  doiwww.sciencedirect.comdoi.org

• Bašica, Branka ; Mihaljević, Ivan ; Maraković, Nikola ; Kovačević, Radmila ; Smital, Tvrtko | Molecular characterization of zebrafish Gstr1, the only member of teleost-specific glutathione S- transferase class // Aquatic toxicology, 208 (2019), 196-207. doi: 10.1016/j.aquatox.2019.01.005

  doiwww.sciencedirect.com

• Kostanjevečki, Petra ; Sviličić Petrić, Ines ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan ; Terzić, Senka | Biodegradation study of methadone by adapted activated sludge: Elimination kinetics, transformation products and ecotoxicological evaluation // Chemosphere, 214 (2019), 719-728. doi: 10.1016/j.chemosphere.2018.09.153

  doiwww.sciencedirect.comdoi.org

• Karaica, Dean ; Breljak, Davorka ; Lončar, Jovica ; Lovrić, Mila ; Micek, Vedran ; Vrhovac Madunić, Ivana ; Brzica, Hrvoje ; Herak-Kramberger, Carol Mirna ; Ivković Dupor, Jana ; Ljubojević, Marija et al. | Sex-independent expression of chloride/formate exchanger Cfex (Slc26a6) in rat pancreas, small intestine, and liver, and male-dominant expression in kidneys // Arhiv za higijenu rada i toksikologiju, 69 (2018), 4; 286-303. doi: 10.2478/aiht-2018-69-3157

  doihrcak.srce.hr

• Terzić, Senka ; Udiković-Kolić, Nikolina ; Jurina, Tamara ; Krizman-Matasić, Ivona ; Senta, Ivan ; Mihaljević, Ivan ; Lončar, Jovica ; Smital, Tvrtko ; Ahel, Marijan | Biotransformation of macrolide antibiotics using enriched activated sludge culture: Kinetics, transformation routes and ecotoxicological evaluation // Journal of hazardous materials, 349 (2018), 143-152. doi: 10.1016/j.jhazmat.2018.01.055

  doiwww.sciencedirect.com

• Lončar, Jovica ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish multidrug and toxin extrusion protein 7 (Mate7/Slc47a7) // Aquatic toxicology, 205 (2018), 193-203. doi: 10.1016/j.aquatox.2018.10.016

  doidoi.org

• Dragojević, Jelena ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | In vitro characterization of zebrafish (Danio rerio) organic anion transporters Oat2a-e // Toxicology in vitro, 46 (2017), 246-256. doi: 10.1016/j.tiv.2017.09.026

  doiwww.sciencedirect.com

• Marić, Petra ; Ahel, Marijan ; Senta, Ivan ; Terzić, Senka ; Mikac, Iva ; Žuljević, Ante ; Smital, Tvrtko | Effect-directed analysis reveals inhibition of zebrafish uptake transporter Oatp1d1 by caulerpenyne, a major secondary metabolite from the invasive marine alga Caulerpa taxifolia // Chemosphere, 174 (2017), 643-654. doi: 10.1016/j.chemosphere.2017.02.007

  doiwww.sciencedirect.com

• Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Maraković, Nikola ; Šinko, Goran ; Smital, Tvrtko | Interaction between zebrafish Oct1 and endo- and xenobiotics // Aquatic toxicology, 187 (2017), 18-28. doi: 10.1016/j.aquatox.2017.03.012

  doiwww.sciencedirect.comdx.doi.org

• Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Smital, Tvrtko | Functional characterization of rainbow trout (Oncorhynchus mykiss) Abcg2a (Bcrp) transporter // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 190 (2016), 15-23. doi: 10.1016/j.cbpc.2016.07.005

  doiwww.sciencedirect.com

• Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Phylogenetic, syntenic, and tissue expression analysis of slc22 genes in zebrafish (Danio rerio) // Bmc genomics, 17 (2016), 626-1-626-13. doi: 10.1186/s12864-016-2981-y

  doibmcgenomics.biomedcentral.com

• Lončar, Jovica ; Popović, Marta ; Krznar, Petra ; Žaja, Roko ; Smital, Tvrtko | The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio) // Scientific reports, 6 (2016), 28937, 15. doi: 10.1038/srep28937

  doiwww.nature.comwww.nature.com

• Glišić, Branka ; Mihaljević, Ivan ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Fent, Karl ; Kovačević, Radmila ; Smital, Tvrtko | Characterization of Glutathione-S-transferases in zebrafish (Danio rerio) // Aquatic toxicology, 158 (2015), 50-62. doi: 10.1016/j.aquatox.2014.10.013

  doiwww.sciencedirect.com

• Ferreira, Marta ; Santosa, Pedro ; Rey-Salgueiroa, Ledicia ; Žaja, Roko ; Reis-Henriques, Maria Armanda ; Smital, Tvrtko | The first demonstration of CYP1A and the ABC protein(s) gene expression and activity in European Seabass (Dicentrarchus labrax) primary hepatocytes // Chemosphere, 100 (2014), 152-159. doi: 10.1016/j.chemosphere.2013.11.051

  doiwww.sciencedirect.com

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish uptake transporter Oatp1d1 (Slco1d1) // Toxicology and applied pharmacology, 280 (2014), 149-158. doi: 10.1016/j.taap.2014.07.015

  doidx.doi.org

• Traven, Luka ; Mićović, Vladimir ; Vukić Lušić, Darija ; Smital, Tvrtko | The responses of the hepatosomatic index (HSI), 7-ethoxyresorufin-O-deethylase (EROD) activity and glutathione-S-transferase (GST) activity in sea bass (Dicentrarchus labrax, Linnaeus 1758) caged at a polluted site: implications for their use in environm // Environmental monitoring and assessment, 185 (2013), 11; 9009-9018. doi: 10.1007/s10661-013-3230-3

  doilink.springer.com

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel Organic anion transporting polypeptide // The Journal of biological chemistry, 288 (2013), 47; 33894-33911. doi: 10.1074/jbc.M113.518506

  doiwww.jbc.orgwww.jbc.org

• Bošnjak, Ivana ; Zaja, Roko ; Sauerborn Klobučar, Roberta ; Šver, Lidija ; Franekić, Jasna ; Smital, Tvrtko | Identification of ABC Transporter Genes in Gonad Tissue of two Mediterranean Sea Urchin Species: Black, Arbacia lixula L., and Rocky, Paracentrotus lividus L. // Bulletin of environmental contamination and toxicology, 91 (2013), 4; 415-419. doi: 10.1007/s00128-013-1021-8

  doilink.springer.com

• Zaja, Roko ; Terzić, Senka ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Ahel, Marijan ; Smital, Tvrtko | Identification of P-Glycoprotein Inhibitors in Contaminated Freshwater Sediments // Environmental science & technology, 47 (2013), 9; 4813-4821. doi: 10.1021/es400334t

  doipubs.acs.org

• Smital, Tvrtko ; Terzić, Senka ; Lončar, Jovica ; Senta, Ivan ; Žaja, Roko ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut-Erik ; Thomas, Kevin V. ; Ahel, Marijan | Prioritisation of organic contaminants in a river basin using chemical analyses and bioassays // Environmental science and pollution research, 20 (2013), 3; 1384-1395. doi: 10.1007/s11356-012-1059-x

  doird.springer.comlink.springer.com

• Della Torre, Camilla ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Focardi, Silvano ; Corsi, Ilaria | Interaction of ABC transport proteins with toxic metals at the level of gene and transport activity in the PLHC-1 fish cell line // Chemico-biological interactions, 198 (2012), 1/3; 9-17. doi: 10.1016/j.cbi.2012.04.008

  doiwww.sciencedirect.com

• Reifferscheid, Georg ; Maes, Hanna ; Allner, Bernhard ; Badurova, Jana ; Belkin, Shimshon ; Blum, Kerstin ; Brauer, Frank ; Bressling, Jana ; Domeneghetti, Stefania ; Elad, Tal et al. | International round-robin study on the Ames fluctuation test // Environmental and molecular mutagenesis, 53 (2012), 3; 185-197. doi: 10.1002/em.21677

  doionlinelibrary.wiley.com

• Žaja, Roko ; Lončar, Jovica ; Popović, Marta ; Smital, Tvrtko | First characterisation of fish P-glycoprotein (abcb1) substrate specificity using determinations of its ATPase activity and calcein-AM assay with PLHC-1/dox cell line // Aquatic toxicology, 103 (2011), 1/2; 53-62. doi: 10.1016/j.aquatox.2011.02.005

  doiwww.sciencedirect.comdoi.org

• Ahel, Marijan ; Mikac, Nevenka ; Smital, Tvrtko | Water resources and wastewater management in the Sava River Basin // Danube News, 13 (2011), 24; 13-15

  www.iad.gs

• Smital, Tvrtko ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Pivčević, Branka ; Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin. V. ; Ahel, Marijan | Assessment of toxicological profiles of the municipal wastewater effluents using chemical analyses and bioassays // Ecotoxicology and environmental safety, 74 (2011), 4; 844-851. doi: 10.1016/j.ecoenv.2010.11.010

  doiwww.sciencedirect.comdoi.org

• Bošnjak, Ivana ; Šegvić, Tanja ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Mladineo, Ivona | Sea Urchin Embryotoxicity Test for Determination of Environmental Contaminants–Potential Role of the MRP Proteins // Water, air and soil pollution, 217 (2011), 1-4; 627-636. doi: 10.1007/s11270-010-0615-6

  doilink.springer.comdoi.org

• Fischer, Stephan ; Lončar, Jovica ; Žaja, Roko ; Schnell, Sabine ; Schirmer, Kristin ; Smital, Tvrtko ; Luckenbach, Till | Constitutive mRNAexpression and protein activity levels of nine ABC efflux transporters in seven permanent cell lines derived from different tissues of rainbow trout (Oncorhynchus mykiss) // Aquatic toxicology, 101 (2011), 2; 438-446. doi: 10.1016/j.aquatox.2010.11.010

  doiwww.sciencedirect.comdoi.org

• Sauerborn Klobučar, Roberta ; Žaja, Roko ; Franjević, Damjan ; Brozović, Anamaria ; Smital, Tvrtko | Presence of Ecotoxicologically Relevant Pgp- and MRP- Transcripts and Proteins in Cyprinid Fish // Arhiv za higijenu rada i toksikologiju, 61 (2010), 2; 175-181

  hrcak.srce.hrhrcak.srce.hr

• Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Organic anion transporting polypeptides (OATP) in zebrafish (Danio rerio): phylogenetic analysis and tissue distribution // Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 155 (2010), 3; 327-335. doi: 10.1016/j.cbpa.2009.11.011

  doidoi.orgwww.sciencedirect.com

• Lončar, Jovica ; Popović, Marta ; Žaja, Roko ; Smital, Tvrtko | Gene expression analysis of the ABC efflux transporters in rainbow trout (Oncorhynchus mykiss) // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 151 (2010), 2; 209-215. doi: 10.1016/j.cbpc.2009.10.009

  doiwww.sciencedirect.comdoi.org

• Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko | A novel ABC transporter: the first insight into zebrafish (Danio rerio) Abch1 // Marine environmental research, 69 (2010), S1; S11-S13. doi: 10.1016/j.marenvres.2009.10.016

  doiwww.sciencedirect.comwww.sciencedirect.com

• Bošnjak, Ivana ; Uhlinger, Kevin R. ; Heim, Wesley ; Smital, Tvrtko ; Franekić Čolić, Jasna ; Coale, Kenneth ; Epel, David ; Hamdoun, Amro | Multidrug Efflux Transporters Limit Accumulation of Inorganic, but Not Organic, Mercury in Sea Urchin Embryos // Environmental science & technology, 43 (2009), 21; 8374-8380. doi: 10.1021/es901677r

  doipubs.acs.org

• Žaja, Roko ; Caminada, Daniel ; Lončar, Jovica ; Fent, Karl ; Smital, Tvrtko | Development and characterization of P-glycoprotein 1 (Pgp1 ; ABCB1) mediated doxorubicin-resistant PLHC-1 hepatoma fish cell line // Toxicology and applied pharmacology, 227 (2008), 2; 207-218. doi: 10.1016/j.taap.2007.11.001

  doiwww.sciencedirect.comwww.sciencedirect.com

• Žaja, Roko ; Munić, Vesna ; Smital, Tvrtko | Cloning and mRNA expression analysis of an ABCG2 (BCRP) efflux transporter in rainbow trout (Oncorhynchus mykiss) liver and primary hepatocytes // Marine environmental research, 66 (2008), 1; 77-79. doi: 10.1016/j.marenvres.2008.02.028

  doiwww.sciencedirect.comdoi.org

• Traven, Luka ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Mićović, Vladimir | CYP1A induction potential and the concentration of priority pollutants in marine sediment samples – In vitro evaluation using the PLHC-1 fish hepatoma cell line // Toxicology in vitro, 22 (2008), 6; 1648-1656. doi: 10.1016/j.tiv.2008.06.012

  doiwww.sciencedirect.comwww.sciencedirect.com

• Epel, David ; Stevenson, Charlotte N. ; MacManus-Spencer, Laura A. ; Luckenbach, Till ; Hamdoun, Amro ; Smital, Tvrtko | Efflux transporters: newly appreciated roles in protection against pollutants // Environmental science & technology, 42 (2008), 11; 3914-3920. doi: 10.1021/es087187v

  doipubs.acs.orgdoi.org

• Žaja, Roko ; Munić, Vesna ; Sauerborn Klobučar, Roberta ; Ambriović-Ristov, Andreja ; Smital, Tvrtko | Cloning and molecular characterization of apical efflux transporters (ABCB1, ABCB11 and ABCC2) in rainbow trout (Oncorhynchus mykiss) hepatocytes // Aquatic toxicology, 90 (2008), 4; 322-332

• Žaja, Roko ; Sauerborn Klobučar, Roberta ; Smital, Tvrtko | Detection and functional characterization of Pgp1 (ABCB1) and MRP3 (ABCC3) efflux transporters in the PLHC-1 fish hepatoma cell line // Aquatic toxicology, 81 (2007), 365-376

• Källqvist, Torsten ; Milačič, Radmila ; Smital, Tvrtko ; Thomas, Kevin V ; Vranes, Sanja ; Tollefsen, Knut-Erik | Chronic toxicity of the Sava River (SE Europe) sediments and river water to the algae Pseudokirchneriella subcapitata // Water research, 42 (2007), 8-9; 2146-2156. doi: 10.1016/j.watres.2007.11.026

  doiwww.sciencedirect.com

• Žaja, Roko ; Klobučar, Goran I.V. ; Sauerborn Klobučar, Roberta ; Hackenberger, Branimir K. ; Smital, Tvrtko | Haemolymph as compartment for efficient and non-destructive determination of Pgp mediated MXR activity in bivalves // Comparative biochemistry and physiology. C. Toxicology & pharmacology, 143 (2006), 1; 103-112-x

• Smital, Tvrtko ; Luckenbach, Till ; Sauerborn, Roberta ; Hamdoun, M. Amro ; Vega, L. Rebecca ; Epel, David | Emerging contaminants - pesticides, PPCPs, microbial degradation products and natural substances as inhibitors of multixenobiotic defense in aquatic organisms // Mutation research, 552 (2004), 101-117-x

• Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Krča, Sanja ; Žaja, Roko ; Jelaska, Dalibor ; Smital, Tvrtko ; Britvić Smiljana | Methods of molecular biology in ecotoxicological research // Periodicum biologorum, 106 (2004), 2; 121-125-x

• Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (mrp) related gene in red mullet (Mullus barbatus) // Marine environmental research, 58 (2004), 2-5; 199-204. doi: 10.1016/j.marenvres.2004.03.120

  doidx.doi.orgwww.sciencedirect.com

• Smital, Tvrtko ; Sauerborn, Roberta ; Hackenberger, Branimir | Inducibility of the multixenobiotic resistance mechanism (MXR) transport activity in the marine mussel Mytilus galloprovincialis and the freshwater mussel Dreissena polymorpha // Aquatic toxicology, 65 (2003), 443-465-x

• Smital, Tvrtko ; Sauerborn, Roberta | Measurement of the activity of multixenobiotic resistance mechanism in the common carp Cyprinus carpio // Marine environmental research, 54 (2002), 3/5; 449-453. doi: 10.1016/S0141-1136(02)00155-1

  doiwww.sciencedirect.comwww.sciencedirect.com

• Ramljak, Sanja ; Hackenberger, Branimir ; Smital, Tvrtko ; Britvić, Smiljana | Evaluation of the genotoxic and cytochrome P450 monooxigenase-inhibitory potential of Dicuran on procaryotic and eucaryotic test systems // Journal of environmental science and health. Part B, 35 (2000), 6; 751-770

• Smital, Tvrtko ; Sauerborn, Roberta ; Pivčević, Branka ; Krča, Sanja ; Kurelec, Branko | Interspecies differences in P-glycoprotein mediated activity of multixenobiotic resistance mechanism in several marine and freshwater invertebrates // Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 126 (2000), 2; 175-186. doi: 10.1016/s0742-8413(00)00110-9

  doiwww.sciencedirect.com

• Osmak, Maja ; Brozović, Anamaria ; Ambriović-Ristov, Andreja ; Hadžija, Mirko ; Pivčević, Branka ; Smital, Tvrtko | Inhibition of apoptosis is the cause of resistance to doxorubicin in human breast adenocarcinoma cells // Neoplasma, 45 (1998), 4; 223-230

  www.ncbi.nlm.nih.gov

• Kurelec, Branko ; Britvić, Smiljana ; Pivčević, Branka ; Smital, Tvrtko | Fragility of multixenobiotic resistance in aquatic organisms enhances the complexity of risk assessment // Marine environmental research, 46 (1998), 1-5; 415-419-x. doi: 10.1016/S0141-1136(97)00065-2

  doiwww.sciencedirect.com

• Smital, Tvrtko ; Kurelec, Branko | The activity of multixenobiotic resistance mechanism determined by rhodamine B-efflux method as a biomarker of exposure // Marine environmental research, 46 (1998), 1-5; 443-447-x. doi: 10.1016/S0141-1136(97)00087-1

  doiwww.sciencedirect.com

• Smital, Tvrtko ; Kurelec, Branko | The concentrations of inhibitors of multixenobiotic resistance mechanism in natural waters: The direct in vivo demonstration of their effect // Environmental toxicology and chemistry, 16 (1997), 10; 2164-2170-x

• Smital, Tvrtko ; Pivčević, Branka ; Kurelec, Branko | Reversal of multidrug resistance by extract from a marine algae Caulerpa taxifolia // Periodicum biologorum, 98 (1996), 2; 197-203

Pregledni rad (znanstveni)

• Kurelec, Branko ; Smital, Tvrtko ; Britvić, Smiljana ; Pivčević, Branka ; Krča, Sanja ; Jelaska, Dalibor ; Balen, Sofija ; Sauerborn, Roberta ; Mustajbegović, Suada | Multixenobiotic resistance mechanism in aquatic organisms // Periodicum biologorum, 99 (1997), 3; 319-328

Ostalo

• Smital, Tvrtko ; Kurelec, Branko | The chemosenzitizers of multixenobiotic resistance mechanism in aquatic invertebrates : a new class of pollutants // Mutation research. Fundamental and molecular mechanisms of mutagenesis, 399 (1998), 1; 43-53-x. doi: 10.1016/S0027-5107(97)00265-0

  doiwww.sciencedirect.com

Prethodno priopćenje

• Kurelec, Branko ; Smital, Tvrtko ; Pivčević, Branka ; Eufemia, Nancy ; Epel, David | Multixenobiotic resistance, P-glycoprotein, and chemosensitizers // Ecotoxicology, 9 (2000), 5; 307-327-x

  www.springerlink.com

Stručni rad

• Smital, Tvrtko ; Lončar, Jovica ; Bakran-Petricioli, Tatjana ; Petricioli, Donat | Pregled recentnih istraživanja usmjerenih određivanju ekotoksikološkog učinka proizvodnih plinskih platformi u sjevernom Jadranu // Naftaplin = Nafta i plin, 36 (2016), 145-146; 89-102

• Bakran-Petricioli, Tatjana ; Smital, Tvrtko ; Petricioli, Donat ; Mlinarić, Damir | Obraštaj na plinskim platformama u Jadranu kao pokazatelj stanja okoliša // Naftaplin = Nafta i plin, 35 (2015), 142; 72-80

  bib.irb.hr

Prikaz, osvrt, kritika

• Smital, Tvrtko | Physiological adaptations of animals in the aquatic environment By Čedomil Lucu // Periodicum biologorum, 116 (2014), 3; 331-333

  hrcak.srce.hr

Pregledni rad (stručni)

• Ahel, Marijan ; Antičić, Tome ; Balog, Tihomir ; Bilić, Nevenko ; Guberina, Branko ; Katušić Hećimović, Silva ; Jerić, Ivanka ; Klanjšček, Tin ; Legović, Tarzan ; Musić, Svetozar et al. | The Ruder Boskovic Institute – Today and Tomorrow // Periodicum biologorum, 112 (2010), 4; 369-374

  hrcak.srce.hr

Sažetak izlaganja sa skupa

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić, Smilja ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | EXPRESSION OF MULTIXENOBIOTIC RESISTANCE IN EUROPEAN HONEYBEE STRAINS (Apis mellifera L.) // Final Programe and Book of Abstract, XXXVIIIth APIMONDIA, International Apicultural Congress, Ljubljana, Slovenia, August 24 - 29. 2003.. | Ljubljana: APIMONDIA, 2003. str. 674-675-x

• Raspor, Biserka ; Erk, Marijana ; Filipović, Vlatka ; Pavičić, Jasenka ; Jurič, Dušica ; Dragun, Zrinka ; Britvić, Smilja ; Krča, Sanja ; Pivčević, Branka ; Smital, Tvrtko et al. | CROWAT projekt : sustav monitoringa okoliša za kopnene vode, estuarije i more u Hrvatskoj // 8. hrvatski biološki kongres s međunarodnim sudjelovanjem : Zbornik sažetaka = 8th Croatian Biological Congress with International Participation : Proceeding of abstracts. | Zagreb: Hrvatsko biološko društvo, 2003. str. 347-348

• Hackenberger K., Branimir ; Smital, Tvrtko ; Britvić-Budicin, Smiljana ; Stepić, Sandra ; Pavlić, Želimira ; Klobučar I.V., Goran | Eksperimentalni organizmi u suvremenom praćenju zagađenja vodenog okoliša / Experimental organisms in modern monitoring water pollution // Prva hrvatska konferencija Hrvatskog društvo kemijskih inženjera i tehnologa - Ekoinženjerstvo 2002 : knjiga sažetaka. | Zagreb, 2002. str. 108-108

• Hackenberger K., Branimir ; Britvić-Budicin, Smiljana ; Smital, Tvrtko ; Stepić, Sandra | The possible influence of some physiological parameters on EROD-activity data valuation // Risk Assessment and Management of Large Contamination Sites : Congress Proceedings. | Halle, 2002

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić-Budučin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Berg, Stefan ; Buchler, Ralph ; Kezić, Nikola | Activity of multixenobiotic resistance mechanism in honeybees // Schedule and Summaries. Molecular Mechanisms of Disease Tolerance in Honeybees.. | Prag, 2000. str. 8-8-x

• Dražić, Marica Maja ; Smital, Tvrtko ; Britvić Budicin, Smiljana ; Krča, Sanja ; Jelaska, Dalibor ; Bubalo, Dragan ; Kezić, Nikola | Multixenobiotic resistance mechanism in honeybees // Report of the 47th seminar in Blaubeuren near Ulm Heinrich-Fabri-Insitut of the Ebergard-Karls-University Tubingen 3-5 April 2000. | Pariz: INRA/DIB-AGIB/EDPm Sciences, 2000. str. 601-601-x

Izvorni znanstveni rad

• Sauerborn, Roberta ; Stupin Polancec, Darija ; Zaja, Roko ; Smital, Tvrtko | Identification of the multidrug resistance-associated protein (MRP) related genes in several marine and freshwater fish species // 12th International Symposium on Pollutant Responses in Marine Organisms (PRIMO12) : conference proceedings. | 2003

Sažetak izlaganja sa skupa

• Karaica, Dean ; Mihaljević, Ivan ; Vujica, Lana ; Dragojević, Jelena ; Bošnjak, Arvena ; Babić, Nency ; Otten Cecile ; Smital, Tvrtko | Improved histological approach for localization and expression analysis of (non)membrane proteins in zebrafish cryosections // FEBS Open Bio, 12, S1, 2022. str. 240-240

• Karaica, Dean ; Breljak, Davorka ; Brzica, Hrvoje ; Lončar, Jovica ; Ljubojević, Marija ; Herak-Kramberger, Carol M. ; Micek, Vedran ; Vrhovac, Ivana ; Ivković Dupor, Jana ; Mihaljević, Ivan et al. | CFEX (Slc26a6) in rat kidneys, liver, and small intestine in an experimental model of oxalate nephrolitiasis // Arhiv za higijenu rada i toksikologiju, 2015. str. 228-228

  hrcak.srce.hrhrcak.srce.hr

• Smital, Tvrtko ; Epel, David ; Britivić, Smiljana ; KrČa, Sanja ; Pivčević, Branka ; Sauerborn Klobučar, Roberta ; Žaja, Roko | Inhibitors of the ABC transport proteins as emerging pollutants— Determination and ecotoxicological relevance // Toxicology letters, 2006. str. S43-S44

  www.sciencedirect.com

• Sauerborn Klobučar, Roberta ; Žaja, Roko ; Smital, Tvrtko | ABC transport proteins as mediators of the multixenobiotic resistance (MXR) defence mechanism in aquatic organisms // The FEBS journal, 2005

  onlinelibrary.wiley.com

Neobjavljeni prilog sa skupa

• Vujica, Lana; Mihaljević, Ivan; Dragojević, Jelena; Lončar, Jovica; Smital, Tvrtko | Phenotype changes in zebrafish Oatp1d1 mutants // Pollutant Responses in Marine Organisms | Nantes, Francuska, 26.05.2024-29.05.2024

  primo22.org

• Lana Vujica, Jovica Lončar, Lana Mišić, Bono Lučić, Katarina Radman, Ivan Mihaljević, Branimir Bertoša , Josip Mesarić, Marina Horvat, Tvrtko Smital | FIRST IN VITRO AND IN SILICO CHARACTERIZATION OF ZEBRAFISH (DANIO RERIO) MULTIDRUG AND TOXIN EXTRUSION PROTEIN 3 (MATE3/SLC47A2.1) // 12th European Zebrafish Meeting | Krakov, Poljska, 09.07.2023-13.07.2023

• Ivanković Koprivić, Klaudija; Dragojević, Jelena; Mihaljević, Ivan; Smital, Tvrtko; Ahel, Marijan; Terzić, Senka | Kinetika akumulacije i eliminacije smjese farmaceutski aktivnih spojeva u modelnom organizmu Danio rerio // Znanstvena škola o okolišu 2023 : Nekonvencionalni pristupi konvencionalnim izazovima | Zagreb, Hrvatska, 27.11.2023-29.11.2023

• Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | INTERACTION OF ENVIRONMENTAL CONTAMINANTS WITH ZEBRAFISH (Danio rerio) MULTIDRUG AND TOXIN EXTRUSION PROTEIN 3 (Mate3/Slc47a3) // HDBMB 2022 Congress – From Science to Knowledge | Brela, Hrvatska, 28.09.2022-01.10.2022

• Vujica, Lana; Mišić, Lana; Horvat, Marina; Lončar, Jovica; Mihaljević, Ivan; Smital, Tvrtko | Interaction of environmental contaminants with zebrafish (Danio rerio) multidrug and toxin extrusion protein 3 (Mate3/Slc47a3) // 21st International Symposium on Pollutant Responses In Marine Organisms (PRIMO21) | Göteborg, Švedska, 22.05.2022-25.05.2022

• Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Mikac, Iva ; Smital, Tvrtko | Comprehensive Scheme for Non-target Screening of Wastewater and Its Application for the Effect- directed Analysis Municipal Sewage // 13th EuCheMS International Conference on Chemistry and the Environment | Zürich, Švicarska, 11.09.2011-15.09.2011

• Della Torre, Camilla ; Lončar, Jovica ; Žaja, Roko ; Focardi Silvano ; Smital, Tvrtko ; Corsi, Ilaria | INVOLVEMENT OF ABC TRANSPORT PROTEINS IN RESPONSE TO TOXIC HEAVY METALS IN THE PLHC-1 FISH CELL LINE // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Popović, Marta ; Žaja, Roko ; Fent, Karl ; Smital, Tvrtko | FIRST CHARACTERIZATION OF ZEBRAFISH (Danio rerio) UPTAKE TRANSPORTERS (Solute Carrier families SLC21 and SLC22) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Glišic, Branka ; Popović, Marta ; Žaja, Roko ; Lončar, Jovica ; Smital, Tvrtko ; Kovačević, Radmila | Phylogenetic and tissue distribution analysis of glutathione-S-transferase family in zebrafish (Danio rerio) // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Smital, Tvrtko ; Žaja, Roko ; Popović, Marta ; Lončar, Jovica | Uptake and efflux transporters versus the adme-tox concept in aquatic toxicology // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Lončar, Jovica ; Žaja, Roko ; Popović, Marta ; Medvedović, Jasna ; Smital, Tvrtko | Tissue distribution and gene expression regulation of MRP9 (abcc12) in rainbow trout and zebrafish // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Žaja, Roko ; Senta, Ivan ; Lončar, Jovica ; Popović, Marta ; Terzić, Senka ; Ahel, Marijan ; Smital, Tvrtko | IDENTIFICATION OF POTENT P-GLYCOPROTEIN (ABCB1) INHIBITORS IN CONTAMINATED SEDIMENT SAMPLES // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Žaja, Roko ; Popović, Marta ; Lončar, Jovica ; Fent, Karl, Smital, Tvrtko | Expression and characterization of rainbow trout (Oncorhynchus Mykiss) BCRP (ABCG2) in SF9 insect cells // Primo 16 - Pollutant Responses in Marine Organisms | Long Beach (CA), Sjedinjene Američke Države, 14.05.2011-18.05.2011

• Ahel, Marijan ; Terzić, Senka ; Žaja, Roko ; Senta, Ivan ; Lončar, Jovica, Popović, Marta ; Mikac, Iva ; Tollefsen, Knut Erik ; Thomas, Kevin V ; Smital, Tvrtko | Relative contribution of polar contaminants to the toxicological profiles of the wastewater effluents of the city of Zagreb (Croatia) // SETAC Europe 20th Annual Meeting | Sevilla, Španjolska, 23.05.2010-27.05.2010

Magistarski rad (znanstveni)

• Stepić, Sandra | Utjecaj oksidativnog stresa na izraženost molekularnih biljega kod babuške (Carassius auratus gibelio) i šarana (Cyprinus carpio) / Hackenberger, Dubravka (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2006

• Smital, Tvrtko | In vivo određivanje koncentracije inhibitora mehanizma multiksenobiotičke otpornosti (MXR) u riječnim vodama / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1998

Doktorski rad

• Dragojević, Jelena | Characterization of organic anion transporters in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2018

• Lončar, Jovica | Function and regulation of ABC transport proteins in rainbow trout (Onchorynchus mykiss) tissues and cell lines / Smital, Tvrtko (mentor). | Zagreb, Sveučilište u Zagrebu, 2015

• Mihaljević, Ivan | Characterization of organic cation transporters in zebrafish (Danio rerio Hamilton, 1882) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015

• Marić, Petra | Ecotoxicological characterization of cyanobacteria and invasive algae from the genus Caulerpa using the concept of effects-directed analyses (EDA) / Smital, Tvrtko (mentor). | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku / Sveučilište u Dubrovniku, 2015

• Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014

  mobi.unios.hr

• Popović, Marta | Identification, characterization and ecotoxicological relevance of membrane transport protein families SLC21 and SLC22 in zebrafish (Danio rerio Hamilton, 1822) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Osijek, Sveučilište Josipa Jurja Strossmayera u Osijeku, Odjel za biologiju, 2014

  mobi.unios.hr

• Bošnjak, Ivana | Zaštitna uloga ABC transportnih proteina tijekom ranog embrionalnog razvoja morskih ježinaca / Smital, Tvrtko ; Šver, Lidija (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010

• Žaja, Roko | Karakterizacija apikalnih transportera ABC u hepatocitima kalifornijske pastrve (Oncorhynchus mykiss) / Smital, Tvrtko (mentor); Smital, Tvrtko (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2010

• Sauerborn Klobučar, Roberta | Karakterizacija mehanizma multiksenobiotičke otpornosti (MXR) vodenih životinja određivanjem MRP-protein kodirajućih gena / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

• Traven, Luka | Ekotoksikološka karakterizacija sedimenata Riječkog zaljeva upotrebom in vitro biotestova / Mićović, Vladimir ; Smital, Tvrtko (mentor). | Rijeka, Medicinski fakultet u Rijeci, 2009

• Smital, Tvrtko | Aktivnost mehanizma multiksenobiotičke otpornosti u vodenih organizama kao pokazatelj kvalitete okoliša / Kurelec, Branko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 1999

Diplomski rad (sveučilišni)

• Bule, Kristina | Određivanje toksičnosti mikroplastike / Kučić Grgić, Dajana ; Smital, Tvrtko (mentor); Miloloža, Martina (neposredni voditelj) . | Zagreb, Fakultet kemijskog inženjerstva i tehnologije, 2020

• Kerkez, Josip | Toksičnost ekstrakata invazivnih tropskih algi roda Caulerpa / Smital, Tvrtko ; Radić Brkanac, Sandra (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2019

  urn.nsk.hr

• Krznar, Petra | Genska ekspresija i filogenija MATE (Multidrug and toxin extrusion) proteina u zebrici, Danio rerio (Hamilton, 1822) / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013

  urn.nsk.hr

• Krznar, Petra | Genska ekspresija i filogenija MATE (Multidrug and toxin extrusion) proteina u zebrici, Danio rerio (Hamilton, 1822) / Smital, Tvrtko; Klobučar, Goran (mentor); Popović, Marta (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2013

  repozitorij.pmf.unizg.hr

• Bartolić, Damir | UTVRĐIVANJE ESTROGENOSTI UZORAKA SEDIMENTA I POVRŠINSKE VODE RIJEKE SAVE BIOTESTOM YES / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2011

• Crnjak, Martina | Utvrđivanje genotoksičnog potencijala uzoraka sedimenta i površinske vode rijeke Save Ames biotestom / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  zir.nsk.hr

• Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak in vitro biotestovima / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  zir.nsk.hrurn.nsk.hr

• Marić, Petra | Estrogeni potencijal i koncentracija inhibitora mehanizma multiksenobiotičke otpornosti u sedimentu potoka Gorjak / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

• Šestak, Ivana | Određivanje toksičnosti uzoraka sedimenta potoka Gorjak biotestovima in vitro / Smital, Tvrtko ; Klobučar, Goran (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2009

  urn.nsk.hr

• Medvedović, Jasna | Molekularna identifikacija i funkcionalna karakterizacija P-glikoproteina (ABCB1) u slatkovodnog školjkaša vrste Unio pictorum (Linnaeus 1758) / Smital, Tvrtko (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2007

Ostali članci/prilozi

• Britvić, Smiljana ; Krča, Sanja ; Kurelec, Branko ; Lucić, Davor ; Pivčević, Branka ; Smital, Tvrtko | Functional and protein expression of multixenobiotic resistance mechanism in a marine mussel as a biomarker of exposure to polluted environments // MAP Technical Report Series No. 103, UNEP, Athens, pp. 29-41, 1998

  wedocs.unep.orgagris.fao.org

Izvještaj

• Raspor, Biserka ; Teskeredžić, Emin ; Smital, Tvrtko ; Picer, Mladen ; Ahel, Marijan | SARIB project Annual Report of Partner 3 (RBI) // Sixth Framework Programme FP6-2002-INCO-WBC-1, 2005

• Raspor, Biserka ; Smital, Tvrtko ; Klobučar, Goran ; Hackenberger, Branimir | An integrated environmental monitoring system for Croatian freshwater, estuarine and coastal marine areas // Research Council of Norway, Project No. 150463, 2005

Član Hrvatskog biološkog društva, Hrvatskog toksikološkog društva i Society of Ecotoxicology and Environmental Safety (SECOTOX).