Projekti

Comparative phosphoproteome analysis of S. rimosus oxytetracycline producers strains

The aim of this project is to determine the role of protein phosphorylation in antibiotic production from industrially important bacterium.

Glavni istraživač: dr. sc. Dušica Vujaklija

Functional characterization of the fungal specific protein Taf14 in S.cerevisiae and C. albicans

Invasive fungal infections have become an important cause of mortality in immunocompromised and severely ill patients, in both the developing world and western countries.

Invertebrate centromere genomics (CENGEN)

The main goal of this project is to identify CenH3 and CenH3-associated DNA sequences as well as their non-functional counterparts in order to explore genomics of differently organized centromeres: satellite DNA-rich, satellite DNA-poor and dispersed on holocentric chromosomes.

Glavni istraživač: dr. sc. Miroslav Plohl

ADP-ribozilacija proteina u modelnom prokariotu Streptomyces coelicolor i čovjeku

Posttranslacijska modifikacija proteina ima važnu ulogu u regulaciji funkcije proteina i interakciji proteina s drugim molekulama. ADP-ribozilacija proteina je posttranslacijska modifikacija kojom se skupina ADP-riboze iz NAD+ prenosi na ciljne proteine.