dr. sc. Dragomira Majhen
Zavod za Molekularnu biologiju
Laboratorij za staničnu biologiju i prijenos signala
Bijenicka 54
10000 Zagreb
Obrazovanje
- 2008. Prirodoslovno matematički fakultet Sveučilišta u Zagrebu: Doktor bioloških znanosti, polje molekularna biologija i biokemija
- 2005. Prirodoslovno matematički fakultet Sveučilišta u Zagrebu: Magistar bioloških znanosti, polje molekularna biologija
- 2001. Prirodoslovno matematički fakultet Sveučilišta u Zagrebu: Diplomirani inžinjer biologije-molekularna biologija
Projekti
2025-2028 HrZZ IP: Sveobuhvatna analiza odgovora stanice domaćina na infekciju adenovirusom čovjeka tip 26
2025-2026 Dokazivanje inovativnog koncepta: ViroSENS: senzor za detekciju bilo kojeg virusa
2024-2026 Podrška transferu tehnologije: VirusHunter-metoda i dijagnostičli komplet za detekciju i identifikaciju virusa
2023-2027 Integrativna karakterizacija novih adenovirusnih vektora namijenjenih za terapijske primjene; Marie Skłodowska-Curie Actions (MSCA)
2023-2024 HR-FR Bilateralni projekt: Razumijevanje proteomske dinamike adenovirusa čovjeka i inficiranih epitelnih stanica
2020-2024 HrZZ IP: Endocitoza adenovirusa i urođeni imunosni odgovor
2018-2019 HR-SLO Bilateralni projekt: Određivanje biokompatibilnosti molibdenovih i volframovih nanočestica - mjerenje citotoksičnosti i upalnog odgovora u in vitro kulturi stanica čovjeka
2016-2017 HAMAG BICRO POC6: VirusHunter - otkrivanje novih potencijalno patogenih virusa
2015-2018 HrZZ UIP: Razumijevanje puta ulaska Adenovirusa tipa 26 u stanicu: način poboljšanja vektora za vakcinaciju
2010-2011 UKF: Deciphering entry pathway of NGR-retargeted adenovirus vectors by confocal microscopy
Nastava
Sudjelovanje u izvođenju nastave Diplomskog i Doktorskog studija u okviru kolegija Genska terapija na Prehrambeno biotehnološkom fakultetu u Zagrebu. Nositelj kolegija je dr. sc. Andreja Ambriović Ristov
Istaknute publikacije
http://www.ncbi.nlm.nih.gov/pubmed/?term=majhen
- Drašković I, Nestić D, Lulić Horvat L, Martinčić J, Stojanović M, Condezo GN, Kašnar K, González-Almela E, Lago D, San Martín C, Custers J, Majhen D. PLoS Pathog. 2026 Aug 10;22(8):e1014028. doi: 10.1371/journal.ppat.1014028.
- Drašković I, Lulić Horvat L, Božinović K, Majhen D. Chapter 17 - Imaging analysis of adenovirus particles during the cell entry and intracellular trafficking Adenoviral Vectors for Gene Therapy (Third Edition) 2025, Pages 501-544, https://doi.org/10.1016/B978-0-323-89821-8.00018-8
- Božinović K, Nestić D, Grellier E, Raddi N, Cornilleau G, Ambriović-Ristov A, Benihoud K, Majhen D. NGR-bearing human adenovirus type 5 infects cells in flotillin- or caveolin-mediated manner depending on the NGR insertion site. Biomater Adv. 2023 Dec;155:213681. doi: 10.1016/j.bioadv.2023.213681.
- Nestić D, Custers J, Švec D, Majhen D. Human Adenovirus Type 26 Infection Mediated by αvβ3 Integrin Is Caveolin-1-Dependent. Microbiol Spectr. 2022 Aug 31;10(4):e0109722.
- Bates EA, Davies JA, Váňová J, Nestić D, Meniel VS, Koushyar S, Cunliffe TG, Mundy RM, Moses E, Uusi-Kerttula HK, Baker AT, Cole DK, Majhen D, Rizkallah PJ, Phesse T, Chester JD, Parker AL. Development of a low-seroprevalence, αvβ6 integrin-selective virotherapy based on human adenovirus type 10. Mol Ther Oncolytics. 2022 Mar 16;25:43-56. doi: 10.1016/j.omto.2022.03.007.
- Nestić D, Božinović K, Drašković I, Kovačević A, van den Bosch J, Knežević J, Custers J, Ambriović-Ristov A, Majhen D. Human Adenovirus Type 26 Induced IL-6 Gene Expression in an αvβ3 Integrin- and NF-κB-Dependent Manner. Viruses. 2022 Mar 24;14(4):672. doi: 10.3390/v14040672.
- Majhen D. Human adenovirus type 26 basic biology and its usage as vaccine vector. Rev Med Virol. 2022 Mar 12:e2338. doi: 10.1002/rmv.2338.
- Nestić D, Hozić A, Brkljača Z, Butorac A, Pažur K, Jullienne B, Cindrić M, Ambriović-Ristov A, Benihoud K, Majhen D. Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency. Life Sci. 2022 Feb 15;291:120116. doi: 10.1016/j.lfs.2021.120116.
- Nestić D, Božinović K, Pehar I, Wallace R, Parker AL, Majhen D. The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal. Pharmaceutics. 2021 Sep 29;13(10):1585. doi: 10.3390/pharmaceutics13101585.
- Nestić D, Uil TG, Ma J, Roy S, Vellinga J, Baker AH, Custers J, Majhen D. αvβ3 Integrin is Required for Efficient Infection of Epithelial Cells with Human Adenovirus Type 26. J Virol. 2018 Oct 17. pii: JVI.01474-18.
- Bressy C, Majhen D, Raddi N, Jdey W, Cornilleau G, Zig L, Guirouilh-Barbat J, Lopez BS, Bawa O, Opolon P, Grellier E, Benihoud K. Combined therapy of colon carcinomas with an oncolytic adenovirus and valproic acid. Oncotarget. 2017 Oct 26;8(57):97344-97360.
- Majhen D, Calderon H, Chandra N, Fajardo CA, Rajan A, Alemany R, Custers J. Adenovirus-based vaccines for fighting infectious diseases and cancer: progress in the field. Hum Gene Ther. 2014 Apr;25(4):301-17.
- Majhen D, Stojanović N, Vukić D, Pichon C, Leduc C, Osmak M, Ambriović-Ristov A. Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation. PLoS One. 2014 Jan 22;9(1):e86698.
- Majhen D, Richardson J, Vukelić B, Dodig I, Cindrić M, Benihoud K, Ambriović-Ristov A. The disulfide bond of an RGD4C motif inserted within the Hi loop of the adenovirus type 5 fiber protein is critical for retargeting to αv -integrins. J Gene Med. 2012 Dec;14(12):788-97.
- Majhen D, Nemet J, Richardson J, Gabrilovac J, Hajsig M, Osmak M, Eloit M, Ambriović-Ristov A. Differential role of alpha(v)beta(3) and alpha(v)beta(5) integrins in internalization and transduction efficacies of wild type and RGD4C fiber-modified adenoviruses. Virus Res. 2009 Jan;139(1):64-73.
- Majhen D, Gabrilovac J, Eloit M, Richardson J, Ambriović-Ristov A. Disulfide bond formation in NGR fiber-modified adenovirus is essential for retargeting to aminopeptidase N. Biochem Biophys Res Commun. 2006 Sep 15;348(1):278-87.
Publikacije - prilozi u knjigama
Stručni rad
Ambriović Ristov, Andreja ; Majhen, Dragomira | Određivanje transkripcijske aktivnosti gena pomoću beta-galaktozidaze // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 514-517-x
Ambriović Ristov, Andreja ; Majhen, Dragomira | Adenovirusi // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 525-538-x
Ostalo
Majhen, Dragomira ; Ambriović Ristov, Andreja | Određivanje koncentracije glutationa // Metode u molekularnoj biologiji. | Zagreb: Institut Ruđer Bošković, 2007. str. 832-836-x
Publikacije - prilozi u časopisima
Izvorni znanstveni rad
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Košćak, Marta ; Pehar, Isabela ; Božinović, Ksenija ; Kumar Kole, Goutam ; Sobočanec, Sandra ; Podgorski, Iva I. ; Pinterić, Marija ; Müller-Buschbaum, Klaus ; Majhen, Dragomira ; Piantanida, Ivo et al. | Para-N-Methylpyridinium Pyrenes: Impact of Positive Charge on ds- DNA/RNA and Protein Recognition, Photo-Induced Bioactivity, and Intracellular Localisation // Pharmaceutics, 14 (2022), 11; 2499, 22. doi: 10.3390/pharmaceutics14112499
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Krošl, Ivona ; Košćak, Marta ; Ribičić, Karla ; Žinić, Biserka ; Majhen, Dragomira ; Božinović, Ksenija ; Piantanida, Ivo | Impact of the Histidine‐Triazole and Tryptophan‐Pyrene Exchange in the WHW Peptide: Cu(II) Binding, DNA/RNA Interactions and Bioactivity // International journal of molecular sciences, 23 (2022), 7006, 24. doi: 10.3390/ijms23137006
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Nestić, Davor ; Hozić, Amela ; Brkljača, Zlatko ; Butorac, Ana ; Pažur, Kristijan ; Jullienne, Betsy ; Cindrić, Mario ; Ambriović-Ristov, Andreja ; Benihoud, Karim ; Majhen, Dragomira | Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency // Life sciences, 291 (2022), 120116, 9. doi: 10.1016/j.lfs.2021.120116
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Nestić, Davor ; Božinović, Ksenija ; Drašković, Isabela ; Kovačević, Alen ; van den Bosch, Jolien ; Knežević, Jelena ; Custers, Jerome ; Ambriović- Ristov, Andreja ; Majhen, Dragomira | Human adenovirus type 26 induced IL-6 gene expression in an αvβ3 integrin- and NF-κB-dependent manner // Viruses, 14 (2022), 4; 672, 16. doi: 10.3390/v14040672
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Bates, Emily A. ; Davies, James A. ; Vanova, Jana ; Nestić, Davor ; Meniel, Valerie S ; Koushyar, Sarah ; Cunliffe, Tabitha G. ; Mundy, Rosie M. ; Moses, Elise ; Uusi-Kerttula, Hanni K. et al. | Development of a low-seroprevalence, αvβ6 integrin-selective virotherapy based on human adenovirus type 10 // Molecular therapy oncolytics, 25 (2022), 43-56. doi: 10.1016/j.omto.2022.03.007
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Kole, Goutam Kumar ; Košćak, Marta ; Amar, Anissa ; Majhen, Dragomira ; Božinović, Ksenija ; Brkljača, Zlatko ; Ferger, Matthias ; Michail, Evripidis ; Lorenzen, Sabine ; Friedrich, Alexandra et al. | Methyl Viologens of Bis-(4'-pyridylethynyl)arenes - Structures, Photophysical and Electrochemical Studies, and their Potential Application in Biology // Chemistry : a European journal, 28 (2022), 40; e202200753, 22. doi: 10.1002/chem.202200753
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Božinović, Ksenija ; Nestić, Davor ; Michail, Evripidis ; Ferger, Matthias ; Košćak, Marta ; Lambert, Christoph ; Majhen, Dragomira ; Marder, Todd B. ; Piantanida, Ivo | Diethynylarene-linked bis(triarylborane)cations as theranostic agents for tumor cell and virus-targeted photodynamic therapy // Journal of photochemistry and photobiology. B, Biology, 234 (2022), 112523, 12. doi: 10.1016/j.jphotobiol.2022.112523
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Čipor, Ivona ; Kurutos, Atanas ; Dobrikov, Georgi M. ; Kamounah, Fadhil S. ; Majhen, Dragomira ; Nestić, Davor ; Piantanida, Ivo | Structure-dependent mitochondria or lysosome-targeting styryl fluorophores bearing remarkable Stokes shift // Dyes and pigments, 206 (2022), 110626, 12. doi: 10.1016/j.dyepig.2022.110626
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Nestić, Davor ; Custers, Jerome ; Švec, Danijel ; Majhen, Dragomira | Human Adenovirus Type 26 Infection Mediated by αvβ3 Integrin Is Caveolin-1-Dependent // Microbiology spectrum, 10 (2022), 4; e01097-22, 17. doi: 10.1128/spectrum.01097-22
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Baranašić, Jurica ; Šutić, Maja ; Catalano, Calogerina ; Drpa, Gordana ; Huhn, Stefanie ; Majhen, Dragomira ; Nestić, Davor ; Kurtović, Matea ; Rumora, Lada ; Bosnar, Martina et al. | TLR5 Variants Are Associated with the Risk for COPD and NSCLC Development, Better Overall Survival of the NSCLC Patients and Increased Chemosensitivity in the H1299 Cell Line // Biomedicines, 10 (2022), 9; 2240, 23. doi: 10.3390/biomedicines10092240
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Belovari, Mateja ; Nestić, Davor ; Marić, Ivan ; Majhen, Dragomira ; Cametti, Massimo ; Džolić, Zoran | Photophysical characterization and the self-assembly properties of mono- and bis-pyrene derivatives for cell imaging applications // New journal of chemistry, 46 (2022), 22518-22524. doi: 10.1039/d2nj03843a
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Berger, Sarina M. ; Rühe, Jessica ; Schwarzmann, Johannes ; Phillipps, Alexandra ; Richard, Ann-Katrin ; Ferger, Matthias ; Krummenacher, Ivo ; Tumir, Lidija-Marija ; Ban, Željka ; Crnolatac, Ivo et al. | Bithiophene-Cored, mono-, bis-, and tris-(Trimethylammonium)- Substituted, bis-Triarylborane Chromophores: Effect of the Number and Position of Charges on Cell Imaging and DNA/RNA Sensing // Chemistry : a European journal, 27 (2021), 14057-14072. doi: 10.1002/chem.202102308
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Orehovec, Iva ; Matković, Marija ; Pehar, Isabela ; Majhen, Dragomira ; Piantanida, Ivo | Bis-Pyrene Photo-Switch Open- and Closed-Form Differently Bind to ds-DNA, ds-RNA and Serum Albumin and Reveal Light-Induced Bioactivity // International journal of molecular sciences, 22 (2021), 4916, 22. doi: 10.3390/ ijms22094916
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Paradžik, Mladen ; Humphries, Jonathan D. ; Stojanović, Nikolina ; Nestić, Davor ; Majhen, Dragomira ; Dekanić, Ana ; Samaržija, Ivana ; Sedda, Delphine ; Weber, Igor ; Humphries, Martin J. et al. | KANK2 links αVβ5 focal adhesions to microtubules and regulates sensitivity to microtubule poisons and cell migration // Frontiers in cell and developmental biology, 8 (2020), 125, 17. doi: 10.3389/fcell.2020.00125
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Božinović, Ksenija ; Nestić, Davor ; Gradišar Centa, Urška ; Ambriović-Ristov, Andreja ; Dekanić, Ana ; de Bisschop, Lenn ; Remškar, Maja ; Majhen, Dragomira | In-vitro toxicity of molybdenum trioxide nanoparticles on human keratinocytes // Toxicology, 444 (2020), 152564, 11. doi: 10.1016/j.tox.2020.152564
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Šmidlehner, Tamara ; Košćak, Marta ; Božinović, Ksenija ; Majhen, Dragomira ; Schmuck, Carsten ; Piantanida, Ivo | Fluorimetric and CD Recognition Between Various ds-DNA/RNA Depends on a Cyanine Connectivity in Cyanine-guanidiniocarbonyl-pyrrole Conjugate // Molecules, 25 (2020), 4470, 14. doi: 10.3390/molecules25194470
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Hulin-Curtis, Sarah L. ; Davies, James A. ; Nestić, Davor ; Bates, Emily A. ; Baker, Alexander T. ; Cunliffe, Tabitha G. ; Majhen, Dragomira ; Chester, John D. ; Parker, Alan L. | Identification of folate receptor α (FRα) binding oligopeptides and their evaluation for targeted virotherapy applications // Cancer gene therapy, 27 (2020), 785-798. doi: 10.1038/s41417-019-0156-0
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Nestić, Davor ; Uil, Taco G. ; Ma, Jiangtao ; Roy, Soumitra ; Vellinga, Jort ; Baker, Andrew H. ; Custers, Jerome ; Majhen, Dragomira | αvβ3 Integrin is Required for Efficient Infection of Epithelial Cells with Human Adenovirus Type 26 // Journal of virology, 93 (2019), 1; e01474, 18. doi: 10.1128/JVI.01474-18
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Stojanović, Nikolina ; Dekanić, Ana ; Paradžik, Mladen ; Majhen, Dragomira ; Ferenčak, Kresimir ; Ruščic, Jelena ; Bardak, Irena ; Supina, Christine ; Tomičić, Maja T. ; Christmann, Markus et al. | Differential effects of integrin αv knockdown and cilengitide on sensitisation of triple-negative breast cancer and melanoma cells to microtubule poisons // Molecular pharmacology, 94 (2018), 6; 1334-1351. doi: 10.1124/mol.118.113027
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Bressy, Christian ; Majhen, Dragomira ; Raddi, Najat ; Jdey, Wael ; Cornilleau, Gaétan ; Zig, Léna ; Guirouilh-Barbat, Josée ; Lopez, Bernard S ; Bawa, Olivia ; Opolon, Paule et al. | Combined therapy of colon carcinomas with an oncolytic adenovirus and valproic acid // Oncotarget, 8 (2017), 8; 97344-97360. doi: 10.18632/oncotarget.22107
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Knežević Teofilović, Natalija ; Bihi, Majjoub ; Radić Stojković, Marijana ; Tumir, Lidija ; Ester, Katja ; Kralj, Marijeta ; Majhen, Dragomira ; Oršolić, Nada ; Lepur, Adriana ; Vrbanec, Damir et al. | 1-ethyl-3-(6-methylphenanthridine-8-il) urea modulates TLR3/9 activation and induces selective pro-inflammatory cytokine expression in vitro // Bioorganic & medicinal chemistry letters, 27 (2017), 7; 1530-1537. doi: 10.1016/j.bmcl.2017.02.048
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Christmann, Markus ; Diesler, Kathrin ; Majhen, Dragomira ; Steigerwald, Christian ; Berte, Nancy ; Freund, Halima ; Stojanović, Nikolina ; Kaina, Bernd ; Osmak, Maja ; Ambriović-Ristov, Andreja et al. | Integrin αVβ3 silencing sensitizes malignant glioma cells to temozolomide by suppression of homologous recombination repair // Oncotarget, 8 (2017), 27754-27771. doi: 10.18632/oncotarget.10897
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Stojanović, Nikolina ; Brozovic, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Fritz, Gerhard ; Osmak, Maja ; Ambriović-Ristov, Andreja | Integrin αvβ3 Expression in Tongue Squamous Carcinoma Cells Cal27 Confers Anticancer Drug Resistance Through Loss of pSrc(Y418) // Biochimica et biophysica acta. Molecular cell research, 1863 (2016), 8; 1969-1978. doi: 10.1016/j.bbamcr.2016.04.019
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Sobočanec, Sandra ; Filić, Vedrana ; Matovina, Mihaela ; Majhen, Dragomira ; Šafranko, Željka Mačak ; Popović Hadžija, Marijana ; Krsnik, Željka ; Gudan Kurilj, Andrea ; Šarić, Ana ; Abramić, Marija et al. | Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo // Redox Biology, 8 (2016), 149-159. doi: 10.1016/j.redox.2016.01.003
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Majhen, Dragomira ; Stojanović, Nikolina ; Vukić, Dunja ; Pichon, Chantal ; Leduc, Chloe ; Osmak, Maja ; Ambriović-Ristov, Andreja | Increased Adenovirus Type 5 Mediated Transgene Expression Due to RhoB Down-regulation // PLoS One, 9 (2014), 1; e86698-x. doi: 10.1371/journal.pone.0086698
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Brozović, Anamaria ; Vuković, Lidija ; Stupin Polančec, Darija ; Arany, Istvan ; Köberle, Beate ; Fritz, Gerhard ; Fiket, Željka ; Majhen, Dragomira ; Ambriović-Ristov, Andreja ; Osmak, Maja | Endoplasmic reticulum stress is involved in response of human laryngeal carcinoma cells to carboplatin but is absent in carboplatin resistant cells // PLoS One, 8 (2013), 9; e763973-1-e763973-12. doi: 10.1371/journal.pone.0076397
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Majhen, Dragomira ; Richardson, Jennifer ; Vukelić, Bojana ; Dodig, Ivana ; Cindrić, Mario ; Benihoud, Karim ; Ambriović-Ristov, Andreja | The disulfide bond of an RGD4C motif inserted within the HI loop of the adenovirus type 5 fiber protein is critical for retargeting to α(v) -integrins // Journal of gene medicine, 14 (2012), 12; 788-797. doi: 10.1002/jgm.2686
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Majhen, Dragomira ; Stojanović, Nikolina ; Špeljko, Tea ; Brozović, Anamaria ; De Zan, Tihana ; Osmak, Maja ; Ambriović-Ristov, Andreja | Increased expression of the coxsackie and adenovirus receptor downregulates alpha v beta 3 and alpha v beta 5 integrin expression, reduces cell adehesion and migration // Life sciences, 89 (2011), 7-8; 241-249. doi: 10.1016/j.lfs.2011.06.009
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Gabrilovac, Jelka ; Čupić, Barbara ; Živković, Emilija ; Horvat, Lucija ; Majhen, Dragomira | Expression, regulation and functional activities of aminopeptidase N (EC 3.4.11.2 ; APN ; CD13) on murine macrophage J774 cell line // Immunobiology, 216 (2011), 1/2; 132-144. doi: 10.1016/j.imbio.2010.06.005
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Majhen, Dragomira ; Brozović, Anamaria ; Buger, Tvrtko ; Gabrilovac, Jelka ; Osmak, Maja ; Ambriović-Ristov, Andreja | Vincristine-resistant human laryngeal carcinoma cells demonstrate increased Rous sarcoma virus promoter activity // Life sciences, 87 (2010), 15/16; 468-474. doi: 10.1016/j.lfs.2010.08.012
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Čubrić Čurik, Vlatka ; Feligini, Maria ; Ferenčaković, Maja ; Džidić, Alen ; Salajpal, Krešimir ; Ambriović-Ristov, Andreja ; Ćetković, Helena ; Majhen, Dragomira ; Čurik, Ino | Sequence polymorphism of PrP exon 3 gene in Istrian and crossbred sheep // Italian Journal of Animal Science, 8 (2009), S3; 86-88
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Majhen, Dragomira ; Nemet, Josip ; Richardson, Jennifer ; Gabrilovac, Jelka ; Hajsig, Martina ; Osmak, Maja ; Eloit, Marc ; Ambriović-Ristov, Andreja | Differential Role OF α vβ 3 and α vβ 5 Integrins in Iinternalization and Transduction Efficacies of Wild Type and RGD4C Fiber-modified Adenoviruses // Virus research, 139 (2009), 1; 64-73. doi: 10.1016/j.virusres.2008.10.004
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Brozović, Anamaria ; Majhen, Dragomira ; Roje, Vibor ; Mikac, Nevenka ; Jakopec, Sanjica ; Fritz, Gerhard ; Osmak, Maja ; Ambriović-Ristov, Andreja | Alpha v beta 3 integrin mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione dependent elimination of drug induced reactive oxidative species // Molecular pharmacology, 74 (2008), 1; 298-306. doi: 10.1124/mol.107.043836
doimolpharm.aspetjournals.orgdoi.org Majhen, Dragomira ; Gabrilovac, Jelka ; Eloit, Marc ; Richardson, Jennifer ; Ambriović-Ristov, Andreja | Disulfide bond formation in NGR fiber-modified adenovirus is essential for retargeting to aminopeptidase N // Biochemical and biophysical research communications, 348 (2006), 278-287-x
Vuković, Lidija ; Ambriović-Ristov, Andreja ; Čimbora Zovko, Tamara ; Ćetković, Helena ; Brozović, Anamaria ; Majhen, Dragomira ; Osmak, Maja | Expression of apoptotic genes in low, clinically relevant levels of drug resistance // Periodicum biologorum, 106 (2004), 2; 173-177-x
Pregledni rad (znanstveni)
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Majhen, Dragomira | Human adenovirus type 26 basic biology and its usage as vaccine vector // Reviews in medical virology, 32 (2022), 6; e2338, 11. doi: 10.1002/rmv.2338
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Schijns, Virgil ; Majhen, Dragomira ; van der Ley, Peter ; Thakur, Aneesh ; Summerfield, Artur ; Berisio, Rita ; Nativi, Cristina ; Fernández- Tejada, Alberto ; Alvarez-Dominguez, Carmen ; Gizurarson, Sveinbjörn et al. | Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation // Pharmaceutics, 13 (2021), 4; 501, 29. doi: 10.3390/pharmaceutics13040501
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Nestić, Davor ; Božinović, Ksenija ; Pehar, Isabela ; Wallace, Rebecca ; Parker, Alan L. ; Majhen, Dragomira | The Revolving Door of Adenovirus Cell Entry: Not All Pathways Are Equal // Pharmaceutics, 13 (2021), 10; 1585, 18. doi: 10.3390/pharmaceutics13101585
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Majhen, Dragomira ; Calderon, Hugo ; Chandra, Naresh ; Fajardo, Carlos Alberto ; Rajan, Anandi ; Alemany, Ramon ; Custers, Jerome | Adenovirus-based vaccines for fighting infectious diseases and cancer: progress in the field // Human gene therapy, 25 (2014), 301-317. doi: 10.1089/hum.2013.235
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Vellinga, Jort ; Smith, J Patrick ; Lipiec, Agnieszka, ; Majhen, Dragomira ; Lemckert, Angelique ; van Ooij, Mark ; Ives, Paul ; Yallop, Christopher ; Custers, Jerome ; Havenga, Menzo | Challenges in manufacturing adenoviral vectors for global vaccine product deployment // Human gene therapy, 25 (2014), 318-327. doi: 10.1089/hum.2014.007
doionline.liebertpub.com Majhen, Dragomira ; Ambriović-Ristov, Andreja | Adenoviral vectors-How to use them in cancer gene therapy? // Virus research, 119 (2006), 121-133-x
Kratko priopćenje
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Ruščić, Jelena ; Ambriović-Ristov, Andreja ; Majhen, Dragomira ; Kolundžija, Silvija ; Barut, Miloš ; Benihoud, Karim ; Krajačić, Mladen | Manipulating adenoviral vector ion-exchange chromatography: Hexon versus fiber // Journal of separation science, 39 (2016), 22; 4299-4304. doi: 10.1002/jssc.201600829
doi
Publikacije - prilozi sa skupa (u zborniku)
Sažetak izlaganja sa skupa
Ambriović-Ristov, Andreja ; Stojanović, Nikolina ; Majhen, Dragomira ; Dekanić, Ana ; Bardak, Irena ; Osmak, Maja | Integrins αvβ3, αvβ5, α3β1 and α4β1 modulate survival upon cisplatin treatment in MDA-MB-435S breast carcinoma cells // EACR-IACR Joint Conference : abstracts ; u: Tumour Microenvironment. | Dublin: EACR, 2012. str. 22-22
Stojanović, Nikolina ; Brozović , Anamaria ; Majhen , Dragomira ; Bressy , Christian ; Benihoud, Karim ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | OVEREXPRESSION OF INTEGRIN αVβ3 IN HUMAN LARYNGEL CARCINOMA (HEp2) AND TONGUE SQUAMOUS CARCINOMA (Cal27) CELLS: ADHESION, MIGRATION, INVASION AND RESISTANCE TO ANTITUMOR DRUGS // Book of Abstracts of the 3rd Congress of Croatian Geneticists with international participation. | 2012
Majhen, Dragomira ; Richardson, Jennifer ; Vukelić, Bojana ; Dodig, Ivana ; Cindrić, Mario ; Benihoud, Karim ; Ambriović-Ristov, Andreja | THE DISULPHIDE BOND OF AN RGD4C MOTIF INSERTED WITHIN THE HI LOOP OF ADENOVIRUS TYPE 5 FIBER PROTEIN IS CRITICAL FOR RETARGETING TO αv-INTEGRINS // Book of Abstracts of the 3rd Congress of Croatian Geneticists with international participation. | 2012
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | OVEREXPRESSION OF αvβ3 AND αvβ5 INTEGRINS IN TONGUE SQUAMOUS CARCINOMA CELLS (Cal27) INHIBITS MIGRATION AND CONFERS RESISTANCE TO SEVERAL ANTITUMOR DRUGS // Book od Abstract FEBS/EACR advanced lecture course : Molecular Mechanisms in Signal Transduction and Cancer, Spetses-Greece, 2011. | 2011
Gabrilovac, Jelka ; Čupić, Barbara ; Zapletal, Emilija ; Horvat, Lucija ; Majhen, Dragomira. | Mannose-receptor-mediated phagocytic activity of aminopeptidase N (EC 3.4.11.2 ; APN ; CD13) on murine macrophage J774 cell line // 2011 Annual Meeting of the Croatian Immunological Society, Book of Abstracts. | Rijeka: Hrvatsko imunološko društvo, 2011. str. 42-42
Špeljko, Tea ; Majhen, Dragomira ; Stojanović, Nikolina ; Brozović, Anamaria ; Vuković, Lidija ; Osmak, Maja ; Ambriović-Ristov, Andreja | The influence of Coxsackie adenovirus receptor expression on integrin expression in human embryonal rhabdomyosarcoma cell line // HDIR-1 From Bench to Clinic First meeting with international participation. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2010. str. 58-58
Brozovic, Anamaria ; Vuković, Lidija ; Stupin Polančec, Darija ; Arany, Istvan ; Köberle, Beate ; Fritz, Gerhard ; Fiket, Željka ; Majhen, Dragomira ; Ambriović-Ristov, Andreja ; Osmak, Maja | Human laryngeal carcinoma cells resistant to carboplatin demonstrate lower constitutive FasL expression and increased expression of atp7a and nhe1 efflux pumps // Book od Abstract HDIR-1 From Bench to Clinic. | Zagreb: Institut Ruđer Bošković, 2010
Vukić, Dunja ; Majhen, Dragomira ; Stojanović, Nikolina ; Brozović, Anamaria ; Osmak, Maja ; Ambriović-Ristov, Andreja | Increased Ad5-mediated transgene expression in cisplatin-resistant human laryngeal carcinoma cells // Book od Abstract HDIR-1 From Bench to Clinic. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2010. str. 38-38
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of integrin αVβ3 in tongue squamous carcinoma cells (CAL27) inhibits migration and confers resistance several antitumor drugs // Book od Abstract HDIR-1 From Bench to Clinic. | Zagreb: Hrvatsko društvo za istraživanje raka (HDIR), 2010. str. 75-75
Majhen, Dragomira ; Richardson, Jennifer ; Vukelić, Bojana ; Vujaklija, Dušica ; Dodig, Ivana ; Cindrić, Mario ; Ambriović-Ristov, Andreja | DISULFIDE BOND FORMED BY CYSTEINES WITHIN RGD4C MOTIF INSERTED IN THE HI LOOP OF ADENOVIRUS TYPE 5 FIBER PROTEIN INFLUENCES ITS RETARGETING POTENTIAL // Book od Abstract HDIR-1 From Bench to Clinic. | 2010
Majhen, Dragomira ; Jelušić, Tihana ; Gabrilovac, Jelka ; Ambriović-Ristov, Andreja | VLA-4 retargeted adenovirus type 5 as vector for acute myeloid leukemia // Targeting and Imaging of tumor microenvironment. Book of Abstracts.. | 2009
Brozović, Anamaria ; Stojanović, Nikolina ; Majhen, Dragomira ; Osmak, Maja ; Ambriović Ristov, Andreja | avß3 integrin mediated drug resistance in human tongue squamous cell carcinoma // Scientific program and abstract book. | Firenza : München, 2009
Majhen, Dragomira ; Richardson, Jennifer ; Ambriović Ristov, Andreja | Cysteines surrounding an RGD motif inserted in the HI loop of human adenovirus type 5 fiber protein influence its retargeting potential // 9th International Adenovirus Meeting. | Dobogóko, 2009. str. 82-82
Ambriović-Ristov, Andreja ; Majhen, Dragomira ; Brozović, Anamaria ; Buger, Tvrtko ; Osmak, Maja | Changes in promoter activity in human laryngeal carcinoma cells resistant to vincristine are responsible for increased adenoviral transgene expression // Abstracts of the 9th International Adenovirus Meeting. | Dobogóko, 2009. str. 60-60
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Osmak, Maja ; Ambriović-Ristov, Andreja | α vβ 3 INTEGRIN MEDIATED DRUG RESISTANCE IN HUMAN TONGUE SQUAMOUS CELL CARCINOMA // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 93-93
Majhen, Dragomira ; Brozović, Anamaria ; Buger, Tvrtko ; Osmak, Maja ; Ambriović-Ristov, Andreja | Increased promoter activity is responsible for increased adenovirus transduction efficacy of human laryngeal carcinoma cells resistant to vincristine // ESGCT 2008 Abstracts, XVIth Annual Congress of the European Society of Gene and Cell Therapy, Concertgebouw, Brugge, Belgium, November 13– 16, 2008. | Mary Ann Liebert, Inc., 2008. str. 1109-1109
Bunoza, Ante ; Majhen, Dragomira ; Brozović, Anamaria ; Osmak, Maja ; Ambriović-Ristov, Andreja | FOCAL ADHESION KINASE IS NOT INVOLVED IN CISPLATIN RESISTANCE OF A HUMAN LARYNGEAL CARCINOMA CELL LINE EXPRESSING α vβ 3 INTEGRIN // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 94-94
Majhen, Dragomira ; Grellier, Elodie ; Ambriović-Ristov, Andreja | THE ABILITY OF RGD4C AND NGR4C TARGETING MOTIFS TO MEDIATE DIRECT INTERNALIZATION OF RETARGETED ADENOVIRUSES // ADENOVIRUSES: BASIC BIOLOGY TO GENE THERAPY. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 28-28
Majhen, Dragomira ; Greiller, Elodie ; Ambriović-Ristov, Andreja | THE ABILITY OF RGD4C AND NGR4C TARGETING MOTIFS TO MEDIATE DIRECT INTERNALIZATION OF RETARGETED ADENOVIRUSES // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 92-92
Bunoza, Ante ; Majhen, Dragomira ; Brozović, Anamaria ; Osmak, Maja ; Ambriović-Ristov, Andreja | FOCAL ADHESION KINASE IS NOT INVOLVED IN CISPLATIN RESISTANCE OF A HUMAN LARYNGEAL CARCINOMA CELL LINE EXPRESSING α vβ 3 INTEGRIN // ADENOVIRUSES: BASIC BIOLOGY TO GENE THERAPY. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 22-22
Osmak, Maja ; Brozović, Anamaria ; Čimbora Zovko, Tamara ; Majhen, Dragomira ; Fritz, Gerhard ; Ambriović Ristov, Andreja | Changes in cell adhesion proteins induced by the treatment with cisplatin and their role in cisplatin-resistance // Abstracts of the 13th World Congress on Advances in Oncology, and 11th International Symposium on Molecular Medicine ; u: International Journal of Molecular Medicine. Supplement. | Atena: Lychnia, Greece, 2008. str. S61-S61
Ambriović-Ristov, Andreja ; Brozović, Anamaria ; Čimbora-Zovko, Tamara ; Majhen, Dragomira ; Gabrilovac, Jelka ; Fritz, Gerhard ; Osmak, Maja | Promjene u adhezijskim proteinima izazvane djelovanjem cisplatine i njihova uloga u otpornosti tumorskih stanica na cisplatinu // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb, 2008. str. 24-24
Jakopec, Sanjica ; Čimbora-Zovko, Tamara ; Dubravčić, Klara ; Garaj-Vrhovac, Verica ; Gajski, Goran ; Sorić, Jasna ; Majhen, Dragomira ; Ambriović Ristov, Andreja ; Osmak, Maja | Stanični odgovor na kurkumin i uzroci otpornosti na ovaj spoj // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb, 2008. str. 89-89
Jelušić, Tihana ; Majhen, Dragomira ; Ambriović-Ristov, Andreja | RETARGETING ADENOVIRUS TYPE 5 TO INTEGRIN α 4β 1 // 50 godina molekularne biologije u Hrvatskoj Zbornik sažetaka. | Zagreb: Institut Ruđer Bošković, 2008. str. 91-91
Majhen, Dragomira ; Brozović, Anamaria ; Gabrilovac, Jelka ; Stojanović, Nikolina ; Osmak, Maja ; Ambriović-Ristov, Andreja | Integrin α Vβ 3 : link between resistance to cisplatin and adenovirus transduction efficacy // Adenoviruses : basic biology to gene therapy : Book of abstracts. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 2-2
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Osmak, Maja ; Ambriović-Ristov, Andreja | α vβ 3 INTEGRIN MEDIATED DRUG RESISTANCE IN HUMAN TONGUE SQUAMOUS CELL CARCINOMA // ADENOVIRUSES: BASIC BIOLOGY TO GENE THERAPY. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 31-31
Jelušić, Tihana ; Majhen, Dragomira ; Ambriović-Ristov, Andreja | RETARGETING ADENOVIRUS TYPE 5 TO INTEGRIN α 4β 1 // ADENOVIRUSES: BASIC BIOLOGY TO GENE THERAPY. | Zagreb: Hrvatsko mikrobiološko društvo, 2008. str. 25-25
Buger, Tvrtko ; Majhen, Dragomira ; Brozović, Anamaria ; Osmak, Maja ; Ambriović-Ristov, Andreja | Changes in promoters activity in human laryngeal carcinoma cells resistant to vincristine are responsible for increased adenoviral transgene expression entered by adenovirus type 5 / Promjene u aktivnosti promotora u ljudskim stanicama karcinoma grkljana otpornima na vinkristin odgovorne su za povećanu ekspresiju transgena unesenog adenovirusom tip 5 // Znanstveni simpozij 50 godina molekularne biologije u Hrvatskoj : program i zbornik sažetaka = Scientific symposium 50 years of molecular biology in Croatia : programme & book of abstracts. | Zagreb: Institut Ruđer Bošković, 2008. str. 90-90
Brozović, Anamaria ; Majhen, Dragomira ; Zisowsky, Jochen ; Jakopec, Sanjica ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of alphaVbeta3 integrin protects human laryngeal carcinoma cell line from cisplatin-induced apoptosis // Mechanisms and Models of Cancer No.2. | 2007
Brozović, Anamaria ; Majhen, Dragomira ; Zisowsky, Jochen ; Jakopec, Sanjica ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of alphaVbeta3 integrin protects human laryngeal carcinoma cell line from cisplatin-induced apoptosis // ELSO 2007 Proceedings. | 2007
Brozović, Anamaria ; Majhen, Dragomira ; Zisowsky, Jochen ; Jakopec, Sanjica ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of alphaVbeta3 integrin protects human laryngeal carcinoma cell line from cisplatin-induced apoptosis // 46th Annual Meeting Program and Abstracts. | 2006
Brozović, Anamaria ; Majhen, Dragomira ; Zisowsky, Jochen ; Jakopec, Sanjica ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of alphaVbeta3 integrin protects human laryngeal carcinoma cell line from cisplatin-induced apoptosis // 14th Euroconference on Apoptosis Programme & Book of Abstracts. | Gent: EDCO, 2006. str. 33-33
Ambriović-Ristov, Andreja ; Majhen, Dragomira ; Hajsig, Martina ; Gabrilovac, Jelka ; Osmak, Maja ; Eloit, Marc ; Richardson, Jennifer | Differential Role OF α vβ 3 and α vβ 5 Integrins in Iinternalization and Transduction Efficacies of Wild Type and RGD4C Fiber-modified Adenoviruses // Abstracts ofg the 8th International Adenovirus Meeting. | Zürich, 2006. str. 69-69
Majhen, Dragomira ; Gabrilovac, Jelka ; Richardson, Jennifer ; Eloit, Marc ; Ambriović-Ristov, Andreja | Differential transduction efficacy of adenoviruses containing NGR within cyclic and linear sequences in HI loop of fiber protein to aminopeptidase N and alpha V beta 3 integrins // Bioscience 2006: Programme and abstracts. | Glasgow, 2006
Majhen, Dragomira ; Gabrilovac, Jelka ; Richardson, Jeniffer ; Eloit, Marc ; Ambriović-Ristov, Andreja | Differential transduction efficacy of adenoviruses containing NGR within cyclic and linear sequences in HI loop of fiber protein to aminopeptidase N and alpha V beta 3 integrins // The FEBS Journal: Abstracts of the 31st FEBS Congress. | Istanbul: Wiley-Blackwell, 2006
Majhen, Dragomira ; Gabrilovac, Jelka ; Eloit, Marc ; Richardson, Jeniffer ; Ambriović-Ristov, Andreja | Disulfide bond formation in NGR fiber-modified adenovirus is essential for retargeting to aminopeptidase N // The 8th International Adenovirus Meeting: Program and Abstracts. | Zürich, 2006
Brozović, Anamaria ; Majhen, Dragomira ; Zisowski, Jochen ; Jakopec, Sanjica ; Osmak, Maja ; Ambriović Ristov, Andreja | Expression of alpha v beta 3 integrin in human laryngeal carcinoma cell line induces drug-resistance to cisplatin, mitomycin C, doxorubicin and nitric oxide // Final programme and book of abstracts. | Zagreb, 2005. str. 45-x
Majhen, Dragomira ; Gabrilovac, Jelka ; Richardson, Jennifer ; Eloit, Marc ; Ambriović-Ristov, Andreja | Adenoviruses Bearing NGR Motifs in the HI-Loop of Adenovirus Fiber Protein Bind Aminopeptidase N and Alpha v Beta 3 Integrins // Structural Basis of Papovavirus Biology. Book of Abstracts. | Siena, 2005. str. 19-19-x
Majhen, Dragomira ; Gabrilovac, Jelka ; Richardson, Jennifer ; Eloit, Marc ; Ambriović-Ristov, Andreja | Vector for Tumor Gene Therapy through Inhibition of Angiogenesis: Adenoviruses Bearing NGR Motifs in the HI-Loop of Adenovirus Fiber Protein Bind Aminopeptidase N and Alpha v Beta 3 Integrins // Abstract book of the XII Annual Congress of the European Society of Gene Therapy. | Tampere, 2004. str. 18-19
Majhen, Dragomira ; Ambriović-Ristov, Andreja ; Eloit, Marc | Vector for tumor gene therapy: Human adenovirus type 5 retargeted on aminopeptidase N // Croatian immunological society 2002 Annual meeting : Book of abstracts. | 2002
Publikacije - prilozi sa skupa (u časopisu)
Sažetak izlaganja sa skupa
Stojanović, Nikolina ; Brozović, Anamaria ; Majhen, Dragomira ; Bressy, Christian ; Benihoud, Karim ; Herak Bosnar, Maja ; Osmak, Maja ; Ambriović-Ristov, Andreja | Overexpression of integrin αvβ3 in human laryngel carcinoma (Hep2) and tongue squamous carcinoma (Cal27) cells: adhesion, migration, invasion and resistance to antitumor drugs // European journal of cancer (1990), 2012. str. S48-S48
Stojanović, Nikolina ; Majhen, Dragomira ; Dekanić, Ana ; Bardak, Irena ; Osmak, Maja ; Ambriović-Ristov, Andreja | Integrins αvβ3, αvβ5, α3β1 and α4β1 modulate survival upon cisplatin treatment in MDA-MB-435S breast carcinoma cells // Periodicum biologorum, 114, S1, 2012. str. 75-75
Publikacije - prilozi sa skupa (neobjavljeni)
Neobjavljeni prilog sa skupa
- Jurković; Marta; Radić Stojković, Marijana; Piantanida, Ivo; Božinović, Ksenija; Majhen, Dragomira; Nestić, Davor; Delgado Pinar, Estefanía; Inclán, Mario; García-España, Enrique | Novel tripodal polyamine tris-pyrene: DNA/RNA binding and photodynamic antiproliferative activity // Multifunctional nanocarriers for nonlinear microscopy: new tools for biology and medicine | Zadar, Hrvatska, 08.06.2026-10.06.2026
- Drašković, Isabela; Vrbančić, Lea; Nestić, Davor; Božinović, Ksenija; Condezo, Gabriela N; San Martin, Carmen; Jerome, Custers; Majhen, Dragomira | Role of Toll-like receptors in innate immune response of epithelial cells after infection with human adenovirus type 26 // 9th European Congress of Virology | Cavtat, Hrvatska, 27.04.2025-30.04.2025
- Kuridža, Bojan; Jurković, Marta; Benicke Rojas, Maria-Victoria; Majhen, Dragomira; Marder, Todd B.; Piantanida, Ivo | New bis-triarylborane chromophores as potential probes for DNA, RNA, and proteins // European Winter School on Physical Organic Chemistry 2025 | Bressanone, Italija, 02.02.2025-07.02.2025
- Drašković, Isabela; Vrbančić, Lea; Nestić, Davor; Božinović, Ksenija; Condezo, Gabriela N.; San Martin, Carmen; Custers, Jerome; Majhen, Dragomira | Recognition of HAdV-D26 by the innate immune system starts already on the cell surface of epithelial cells // 16th International Adenovirus Meeting | Cardiff, Ujedinjeno Kraljevstvo, 07.07.2025-11.07.2025
- Belovari, Mateja; Majhen, Dragomira; C. Hayes, Sophia; Piantanida, Ivo | Novel Cyanine-Styryl Conjugates for ds-DNA/RNA Recognition and cellular bioimaging // 2nd LUCES GLobal Action Meeting | Zadar, Hrvatska, 28.04.2025-29.04.2025
- Tomić, Marija ; Stojanović, Nikolina ; Rac, Anja ; Coopmans, Kaatje ; Majhen, Dragomira ; Humphries, Jon D. ; Humphries, Martin J. ; Ambriović-Ristov, Andreja | Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration // Fibronectin, Integrins and Related Molecules Gordon Research Conference The Biology of Integrins and the Extracellular Matrix | Ventura, Sjedinjene Američke Države, 04.02.2023-10.02.2023
- Lončarić, Marija ; Stojanović, Nikolina ; Rac Justament, Anja ; Coopmans, Kaatje ; Majhen, Dragomira ; Humphries, Jonathan D. ; Humphries, Martin J. ; Ambriović-Ristov, Andreja | Proteini αVβ5 fokalnih adhezija u odgovoru na tretman kemoterapeutikom paklitakselom u staničnoj liniji melanoma // 8. simpozij Apoptoza i novotvorine | Zagreb, Hrvatska, 19.06.2023-19.06.2023
- Drašković, Isabela; Nestić, Davor; Majhen, Dragomira; Lulić-Horvat, Lucija | Intracellular trafficking of human adenovirus type 26 // 15th International Adenovirus Meeting, 24-28 September 2023, Brač Island, Croatia | Bol, Hrvatska, 24.09.2023-28.09.2023
- Drašković, Isabela; Nestić, Davor; Majhen, Dragomira; Božinović, Ksenija | Solving the mystery: innate immunity, HAdV-D26, and epithelial cells // 15th International Adenovirus Meeting, 24-28 September 2023, Brač Island, Croatia | Bol, Hrvatska, 24.09.2023-28.09.2023
- Lončarić, Marija; Stojanović, Nikolina; Rac, Anja; Coopmans, Kaatje; Majhen, Dragomira; Humphries, Jonathan D.; Humphries, Martin J.; Ambriović Ristov, Andreja | Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line // Adhere1 | Zadar, Hrvatska, 06.09.2023-09.09.2023
- Lončarić, Marija; Stojanović, Nikolina; Rac Justament, Anja; Coopmans, Kaatje; Majhen, Dragomira; Humphries, Jonathan D. ; Humphries, Martin J.; Ambriović‑Ristov, Andreja | Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA‑MB‑435S melanoma cell line // The International Conference on Multimodality Therapy of Tumor | Dalian, Kina, 02.12.2023-05.12.2023
- Davor Nestić, Ksenija Božinović, Isabela Pehar, Alen Kovačević, Jolien van den Bosch, Jelena Knežević, Jerome Custers, Andreja Ambriović Ristov, Dragomira Majhen | Adenoviral infection elicits a significant and diverse innate immune response in human epithelial cells // 14th International Adenovirus Meeting | Španjolska, 18.05.2021-21.05.2021
- Nestić, Davor ; Custers, Jerome ; Majhen, Dragomira | Role of clathrin and caveolin in human adenovirus type 26 cell entry // 14th International Adenovirus Meeting | Španjolska, 18.05.2021-21.05.2021
- Majhen, Dragomira; Nestić, Davor | Human adenovirus type 26 infection of epithelial cells is αvβ3 integrin, clathrin and caveolin-1 mediated // 14th International Adenovirus Meeting | Španjolska, 18.05.2021-21.05.2021
Publikacije - ocjenski radovi
Diplomski rad (sveučilišni)
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Kašnar, Klara | Uloga Rab proteina u uspješnosti transdukcije adenovirusom tipa 26 / Majhen, Dragomira (mentor); Nestić, Davor (neposredni voditelj) . | Zagreb, 2022
urn.nsk.hr Vrbančić, Lea | Uloga endocitoze posredovane klatrinom u ekspresiji upalnih citokina nakon infekcije adenovirusom tipa 26 / Majhen, Dragomira ; Černi, Silvija (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2021
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Lindić, Petra | Uloga klatrina u infekciji adenovirusnim vektorima tipa 5, 26 i 35 / Majhen, Dragomira (mentor). | Zagreb, 2021
urn.nsk.hr Švec, Danijel | Utjecaj utišavanja kaveolina-1 na uspješnost transdukcije adenoviralnim vektorima tipa 5, 26 i 35 / Majhen, Dragomira (mentor); Nestić, Davor (neposredni voditelj) . | Zagreb, Prehrambeno-biotehnološki fakultet, 2020
Slijepčević, Marijana | Utjecaj utišavanja Toll sličnog receptora 9 na poticanje urođenog imunosnog odgovora nakon infekcije s adenoviralnim vektorom 26 / Majhen, Dragomira (mentor); Nestić, Davor (neposredni voditelj) . | Zagreb, Prehrambeno-biotehnološki fakultet, 2018
Radić, Ivana | Usporedba aktivacije urođenog imunosnog odgovora u stanicama monocita i mišića čovjeka nakon infekcije adenovirusima tipa 5, 26 i 35 / Majhen, Dragomira (mentor); Nestić, Davor (neposredni voditelj) . | Zagreb, Prehrambeno-biotehnološki fakultet, 2018
Van den Bosch, Jolien | Measuring inflammasome activation after adenovirus infection / Majhen, Dragomira (mentor); Nestić, Davor (neposredni voditelj) . | Ghent, 2017
Nestić, Davor | ODREĐIVANJE PRISUTNOSTI DISULFIDNIH VEZA U NGR PREUSMJERAVAJUĆEM SLIJEDU UGRAĐENOM U VLAKNO ADENOVIRUSNOG VEKTORA / Majhen, Dragomira (mentor). | Zagreb, Prehrambeno-biotehnološki fakultet, 2015
Majhen, Dragomira | Određivanje primarne strukture gena smještenih u neposrednoj blizini gena recA iz bakterije Streptomyces rimosus / Gamulin, Vera (mentor); Mikoč, Andreja (neposredni voditelj) . | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2001
Magistarski rad (znanstveni)
Majhen, Dragomira | Preusmjeravanje adenovirusa tip 5 na aminopeptidazu N / Ambriović Ristov, Andreja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2005
Doktorski rad
Nestić, Davor | Karakterizacija ulaska adenovirusa tipa 26 u stanice epitela čovjeka / Majhen, Dragomira (mentor). | Zagreb, Sveučilište Josipa Jurja Strossmayera u Osijeku, 2020
Majhen, Dragomira | AUGMENTATION OF ADENOVIRUS TRASNDUCTION: CHANGING EXPRESSION OF NATURAL RECEPTORS AND RETARGETING TO NEW ONES / Povećanje djelotvornosti transdukcije adenovirusima: promjena ekspresije prirodnih receptora i preusmjeravanje na nove receptore / Ambriović Ristov, Andreja (mentor). | Zagreb, Prirodoslovno-matematički fakultet, Zagreb, 2008
Članstva u profesionalnim udrugama / društvima
- član "Hrvatskog društva za biokemiju i molekularnu biologiju"
- član "Hrvatskog mikrobiološkog društva"
- član "Hrvatskog društva za istraživanje raka"
- član "Francuskog društva za Gensku i staničnu terapiju“
Stipendije, usavršavanja i boravci u stranim institucijama:
- 2013-2014 Crucell Holland BV, Nizozemska, industrijsko poslijedoktorsko usavršavanje u okviru FP7 Marie Curie ITN ADVance programa
- 2010-2012 CNRS UMR8203 IGR Villejuif, Francuska; poslijedoktorsko usavršavanje; Gaining Experience Grant, Unity Through Knowledge Fund, Stipendija Hrvatske zaklade za znanosti
- 2009. UMR 1161 Virologie INRA-AFSSA- ENVA, Ecole Nationale Veterinaire, Maisons Alfort, Francuska; Boehringer Ingelheim travel grant
- 2007. INSERM U 524, Institute de Recherche sur le Cancer, Lille, Francuska; Stipendija Ministarstva za znanost, obrazovanje i sport Republike Hrvatske
- 2006. INSERM U 524, Institute de Recherche sur le Cancer, Lille, Francuska; FEMS kratkotrajna stipendija
- 2004. UMR 1161 Virologie INRA-AFSSA- ENVA, Ecole Nationale Veterinaire, Maisons Alfort, Francuska; Stipendija Francuske vlade
- 2003. UMR 1161 Virologie INRA-AFSSA- ENVA, Ecole Nationale Veterinaire, Maisons Alfort, Francuska; EMBO kratkotrajna stipendija
Povjerenstva, odbori i radne skupine:
- 2019- Marie Curie Alumni Association Croatian Chapter Chair
- 2010. član radne skupine Instituta Ruđer Bošković za suradnju sa Sveučilištem u Zagrebu
- 2010. predstavnica Vijeća asistenata u Znanstvenom vijeću Instituta Ruđer Bošković
- 2005-2006. zamjenica predsjednika Vijeća asistenata
- 2005-2010. predstavnica asistenata Zavoda za molekularnu biologiju u Vijeću asistenata Instituta Ruđer Bošković
- 2005-2010. član upravnog odbora poslijediplomske udruge "Mreža mladih znanstvenika", MLAZ
Organizacijske vještine i kompetencije:
- 2013-2014. član organizacijskog odbora škole "Power of Viral Vectors in Gene Therapy and Basic Science" http://hmd-cms.hr/viral-vectors/
- 2007-2014. član Savjetodavnog odbora festivala "Festival of Conversation for Culture and Science" http://www.flow-festival.com/
- 2007-2008. član organizacijskog odbora škole "Adenoviruses basic biology to gene therapy" www.hmd-cms.hr/adenoviruses/index.html
- 2002-2003. voditeljica "Mladih istraživača", sekcije Hrvatskog prirodoslovnog društva